Dimethyl [anilino(4-fluorophenyl)methyl]phosphonate

Base Information

Chemical Name:Dimethyl [anilino(4-fluorophenyl)methyl]phosphonate
CAS No.:141380-76-9
Molecular Formula:C15H17FNO3P
Molecular Weight:309.277
Hs Code.:
DSSTox Substance ID:DTXSID30576844
Nikkaji Number:J458.108C
Mol file:141380-76-9.mol

Synonyms:141380-76-9;Dimethyl [anilino(4-fluorophenyl)methyl]phosphonate;DTXSID30576844

Suppliers and Price of Dimethyl [anilino(4-fluorophenyl)methyl]phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Dimethyl [anilino(4-fluorophenyl)methyl]phosphonate

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:309.09300856
Heavy Atom Count:21
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COP(=O)(C(C1=CC=C(C=C1)F)NC2=CC=CC=C2)OC

Technology Process of Dimethyl [anilino(4-fluorophenyl)methyl]phosphonate

There total 4 articles about Dimethyl [anilino(4-fluorophenyl)methyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 67-56-1
methanol

: 5676-81-3,102904-34-7
4-fluorobenzalaniline

: 141380-76-9
dimethyl ((4-flurophenyl)(phenylamino)methyl)phosphonate

Guidance literature:: With phosphorus trichloride; In dichloromethane; at 0 ℃; for 0.25h;
DOI:10.1055/s-1992-26083

Reference yield: 91.0%

: 459-57-4
4-fluorobenzaldehyde

: 62-53-3
aniline

: 121-45-9
phosphorous acid trimethyl ester

: 141380-76-9
dimethyl ((4-flurophenyl)(phenylamino)methyl)phosphonate

Guidance literature:: With Lipase B Candida Antarctica immobilized on immobead 150 recombinant from yeast; In acetonitrile; at 20 ℃; for 0.583333h; Green chemistry;
DOI:10.1007/s11164-021-04535-2