Thiazolidine, hydrochloride (1:1)

Base Information

• Chemical Name: Thiazolidine, hydrochloride (1:1)
• CAS No.: 14446-47-0
• Molecular Formula: C3H7NS.ClH
• Molecular Weight: 125.622
• Hs Code.: 2934999090
• Mol file: 14446-47-0.mol

Synonyms:thiazolidine, hydrochloride;thiazolidinium chloride;Thiazolidin, Hydrochlorid;

Chemical Property of Thiazolidine, hydrochloride (1:1)

Chemical Property:

• Melting Point: 180 °C(Solv: water (7732-18-5))
• PSA: 37.33000
• LogP: 1.41110

Purity/Quality:

97% ^*data from raw suppliers

ThiazolidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Thiazolidine, hydrochloride (1:1)

There total 1 articles about Thiazolidine, hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-mercaptoethylamine hydrochloride (156-57-0) → thiazolidine hydrochloride (14446-47-0)

Guidance literature:

In water; at 20 ℃;

DOI:10.1016/j.bbrc.2010.11.052

Reference yield: 85.1%

thiazolidine hydrochloride (14446-47-0) + N-tert-butoxycarbonyl-4-oxo-L-proline (84348-37-8) → (2S)-4-oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic acid tert-butyl ester (401564-36-1)

Guidance literature:

N-tert-butoxycarbonyl-4-oxo-L-proline; With triethylamine; In dichloromethane; at -5 - 5 ℃; for 0.5h;

thiazolidine hydrochloride; With pivaloyl chloride; triethylamine; In dichloromethane; at -5 - 5 ℃; for 4h;

Reference yield: 63.0%

thiazolidine hydrochloride (14446-47-0) → β-methylaminoethanethiol hydrochloride (33744-33-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Inert atmosphere; Reflux;

DOI:10.1016/j.bbrc.2010.11.052

upstream raw materials:

formaldehyd

2-mercaptoethylamine hydrochloride

Downstream raw materials:

3-(4-nitro-benzenesulfonyl)-thiazolidine

[1-(4-azido-cyclohexyl)-2-oxo-2-thiazolidin-3-yl-ethyl]-carbamic acid tert-butyl ester

1-phenyl-3-thiazolidin-3-yl-propan-1-one

5-phenethyl-2,3,4,7-tetrahydro[1,4]thiazepine-6-carbonitrile