1,4-Benzenedimethanol, diacetate

Base Information

• Chemical Name: 1,4-Benzenedimethanol, diacetate
• CAS No.: 14720-70-8
• Molecular Formula: C12H14O4
• Molecular Weight: 222.241
• Mol file: 14720-70-8.mol

Synonyms:1,4-bis-acetoxymethyl-benzene;1,4-Bis-acetoxymethyl-benzol;1,4-Benzenedimethanol,diacetate;

Chemical Property of 1,4-Benzenedimethanol, diacetate

Chemical Property:

• Melting Point: 48-49 °C
• Boiling Point: 180-185 °C(Press: 20 Torr)
• PSA: 115.06000
• Density: 1.139±0.06 g/cm3(Predicted)
• LogP: 0.85300

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-Benzenedimethanol, diacetate

There total 15 articles about 1,4-Benzenedimethanol, diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,4-bis(trimethylsilyloxymethyl)benzene (2117-22-8) + acetic anhydride (108-24-7) → 1,4-bis(hydroxymethyl)benzene diacetate (14720-70-8)

Guidance literature:

With montmorillonite K-10; for 0.25h;

Reference yield: 50.0%

para-xylene (106-42-3) → p-tolylmethylenediacetate (2929-93-3) + p-methylbenzyl alcohol acetate (2216-45-7) + 1,4-bis(hydroxymethyl)benzene diacetate (14720-70-8)

Guidance literature:

With sodium persulfate; copper diacetate; sodium acetate; In acetic acid; Mechanism; Heating; other molar ratio of oxidizing agent;

DOI:10.1055/s-1980-29061

Reference yield: 44.0%

p-methylbenzyl alcohol acetate (2216-45-7) → 1,4-bis(hydroxymethyl)benzene diacetate (14720-70-8) + 4-(acetoxymethyl)benzaldehyde (54549-74-5) + 4-methyl-benzaldehyde (104-87-0) + p-Toluic acid (99-94-5)

Guidance literature:

With copper diacetate; cobalt(II) acetate; acetic acid; sodium bromide; at 150 ℃; for 1h; under 29420.3 Torr; Further byproducts given;

DOI:10.1246/bcsj.54.2724

upstream raw materials:

p-methylbenzyl alcohol acetate

acetic acid

1,4-bis(bromomethyl)benzene

para-xylene

Downstream raw materials:

methyl (Z)-2-(acetylamino)-3-[4-(acetoxymethyl)phenyl]propenoate

methyl (Z)-2-(acetylamino)-3-[4-(hydroxymethyl)phenyl]propenoate

(Z)-2-(acetylamino)-3-[4-(hydroxymethyl)phenyl]propenoic acid

methyl (2R)-2-(acetylamino)-3-[4-(acetoxymethyl)phenyl]propanoate