1,3-bis(4-tert-butylphenyl)urea

Base Information

• Chemical Name: 1,3-bis(4-tert-butylphenyl)urea
• CAS No.: 78015-86-8
• Molecular Formula: C21H28 N2 O
• Molecular Weight: 324.466
• Mol file: 78015-86-8.mol

Synonyms:Carbanilide,4,4'-di-tert-butyl- (6CI); NSC 35976

Chemical Property of 1,3-bis(4-tert-butylphenyl)urea

Chemical Property:

• Vapor Pressure: 1.12E-05mmHg at 25°C
• Boiling Point: 370.2°C at 760 mmHg
• Flash Point: 90.5°C
• Density: 1.07g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-bis(4-tert-butylphenyl)urea

There total 9 articles about 1,3-bis(4-tert-butylphenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

trifluoromethyl trifluoromethanesulfonate (3582-05-6) + 4-tert-Butylaniline (769-92-6) → 1,3-bis(4-(tert-butyl)phenyl)urea (78015-86-8)

Guidance literature:

In acetonitrile; at 20 ℃; for 1h; Sealed tube;

DOI:10.1002/chem.201901865

Reference yield: 86.0%

carbon dioxide (124-38-9,18923-20-1) + 4-tert-Butylaniline (769-92-6) → 1,3-bis(4-(tert-butyl)phenyl)urea (78015-86-8)

Guidance literature:

With iron(III) chloride; phenylsilane; 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; In tetrahydrofuran; at 110 ℃; for 22h; under 760.051 Torr; Sealed tube;

DOI:10.1021/acs.joc.0c02032

Reference yield: 82.0%

carbon monoxide (201230-82-2) + 4-tert-Butylaniline (769-92-6) → 1,3-bis(4-(tert-butyl)phenyl)urea (78015-86-8)

Guidance literature:

With oxygen; potassium iodide; In neat (no solvent); at 122 ℃; for 6h; Green chemistry;

DOI:10.1039/c9gc01577a

upstream raw materials:

phosgene

4-tert-Butylaniline

ethanol

1,3-di(p-tert-butylphenyl)carbodiimide

Downstream raw materials:

methanol

4-tert-Butylaniline