1,2,4-Trimethyl-1H-imidazole

Base Information

Chemical Name:1,2,4-Trimethyl-1H-imidazole
CAS No.:1842-63-3
Molecular Formula:C6H10N2
Molecular Weight:110.159
Hs Code.:
DSSTox Substance ID:DTXSID20563329
Nikkaji Number:J2.270.048K
Wikidata:Q82447750
Mol file:1842-63-3.mol

Synonyms:1,2,4-Trimethyl-1H-imidazole;1842-63-3;1,2,4-trimethylimidazole;1H-Imidazole, 1,2,4-trimethyl-;SCHEMBL486467;DTXSID20563329;AGMJWUBJIPQHBM-UHFFFAOYSA-N;MFCD22055187;E89160;EN300-224733

Suppliers and Price of 1,2,4-Trimethyl-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 1,2,4-Trimethyl-1H-imidazole

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:110.084398327
Heavy Atom Count:8
Complexity:82.6

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C(=N1)C)C

Technology Process of 1,2,4-Trimethyl-1H-imidazole

There total 2 articles about 1,2,4-Trimethyl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 693-98-1
2-methylimidazole

: 1739-84-0
1,2-dimethyl-1H-imidazole

: 1739-83-9
1,2,4,5-tetramethylimidazole

: 1842-63-3
1,2,4-trimethylimidazole

Guidance literature:: γ-Al2O3; at 350 - 400 ℃; Product distribution; other catalysts, var. temp., other alkohols;
DOI:10.1007/BF01169831

Reference yield:

: 66-27-3
Methyl methanesulfonate

: 930-62-1
2,4-Dimethylimidazole

: 1739-81-7
1,2,5-Trimethyl-imidazol

: 1842-63-3
1,2,4-trimethylimidazole

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 16h; Inert atmosphere;

Reference yield:

: 1842-63-3
1,2,4-trimethylimidazole

: N-(imidazo[1,2-a]pyridin-6-ylmethyl)-N-methyl-5-(2-methyl-4-(1,2,4-trimethyl-1H-imidazol-5-yl)phenyl)-1,3,4-oxadiazol-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / tetrahydrofuran / 4 h

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / 1,4-dioxane; water / 12 h / 90 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; N-iodo-succinimide; sodium carbonate; In tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1021/acs.jmedchem.1c00920