1-Hydroxycarbazole

Base Information

• Chemical Name: 1-Hydroxycarbazole
• CAS No.: 61601-54-5
• Molecular Formula: C12H9 N O
• Molecular Weight: 183.21
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID10210618
• Nikkaji Number: J1.159.963J
• Wikidata: Q83085373
• Mol file: 61601-54-5.mol

Synonyms:9H-carbazol-1-ol;1-Hydroxycarbazole;61601-54-5;CCRIS 5299;hydroxycarbazole;9H-Carbazole-1-ol;SCHEMBL329557;DTXSID10210618;AKOS006276059;CS-16514;LS-188681;CS-0099230;D72061

Chemical Property of 1-Hydroxycarbazole

Chemical Property:

• Vapor Pressure: 4.78E-08mmHg at 25°C
• Melting Point: 164 °C
• Boiling Point: 431.4°Cat760mmHg
• PKA: 10.10±0.30(Predicted)
• Flash Point: 214.7°C
• PSA: 36.02000
• Density: 1.362g/cm³
• LogP: 3.02670
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 183.068413911
• Heavy Atom Count: 14
• Complexity: 218

Purity/Quality:

99.0% ^*data from raw suppliers

1-HYDROXYCARBAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(N2)C(=CC=C3)O

Technology Process of 1-Hydroxycarbazole

There total 4 articles about 1-Hydroxycarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.3%

9H-carbazole (86-74-8,105184-46-1,97960-57-1) → 1-hydroxycarbazole (61601-54-5) + 2'-aminobiphenyl-2,3-diol (148519-91-9)

Guidance literature:

With Escherichia coli JM₁₀₉ harbouring pJ₃₁BP-Q₂₈₂Y; In dimethyl sulfoxide; at 30 ℃; for 18h; L-medium; Enzymatic reaction;

DOI:10.1271/bbb.80512

Reference yield:

1-(2-nitrophenyl)-1H-benzo[d][1,2,3]triazole (2229-36-9) → 1-hydroxycarbazole (61601-54-5) + 1-nitro-9H-carbazole (31438-22-9) + 9H-carbazole (86-74-8,105184-46-1,97960-57-1)

Guidance literature:

at 500 ℃;

Reference yield:

1-oxo-2,3,4,9-tetrahydrocarbazole (3456-99-3) → 1-hydroxycarbazole (61601-54-5) + 9H-carbazole (86-74-8,105184-46-1,97960-57-1)

Guidance literature:

at 245 ℃; Kohlendioxid-Atmosphaere;

DOI:10.1039/jr9550003475

upstream raw materials:

1-(2-nitrophenyl)-1H-benzo[d][1,2,3]triazole

1-oxo-2,3,4,9-tetrahydrocarbazole

9H-carbazole

Downstream raw materials:

1-ethoxy-9H-carbazole

1-aminocarbazole