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Tetracaine

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Name

Tetracaine

EINECS 202-316-6
CAS No. 94-24-6 Density 1.044 g/cm3
Solubility Melting Point
Formula C15H24N2O2 Boiling Point 389.4 °C at 760 mmHg
Molecular Weight 264.36 Flash Point 189.3 °C
Transport Information UN 2811 Appearance
Safety 22-36/37 Risk Codes 22-40-42/43-43
Molecular Structure Molecular Structure of 94-24-6 (Tetracaine) Hazard Symbols HarmfulXn, IrritantXi
Synonyms

Benzoicacid, p-(butylamino)-, 2-(dimethylamino)ethyl ester (8CI);2-Dimethylaminoethylp-butylaminobenzoate;Amethocaine;Ametop;Anetain;Butylocaine;Contralgin;Fissucain;Intercain;Laudocaine;Medicaine;Medihaler-Tetracaine;Meethobalm;Metraspray;Mucaesthin;Pontocaine;Rexocaine;Uromucaesthin;b-Dimethylaminoethylp-N-butylaminobenzoate;b-Dimethylaminoethyl p-butylaminobenzoate;

 

Tetracaine Chemical Properties

Product Name: Tetracaine (CAS NO.94-24-6)

Molecular Formula: C15H24N2O2     
Molecular Weight: 264.36g/mol
Density:1.044 g/cm 
Boiling point:389.4 °C at 760 mmHg 
Flash point:189.3 °C    
Index of Refraction:1.537 
Molar Refractivity:79.15 cm3 
Molar Volume:253 cm3
Polarizability:31.37 10-24cm3
Surface Tension:39.7 dyne/cm
Enthalpy of Vaporization:63.87 kJ/mol  
Vapour Pressure:2.87E-06 mmHg at 25°
IUPAC Name: 2-dimethylaminoethyl 4-(butylamino)benzoate
Product Categories: API

Tetracaine Uses

 It's used as narcotic drugs.

Tetracaine Toxicity Data With Reference

1.    

dnd-esc 30 µmol/L

    MUREAV    Mutation Research. 89 (1981),95.
2.    

dns-hmn:hla 1 µmol/L

    BCPCA6    Biochemical Pharmacology. 14 (1965),205.
3.    

par-man LDLo:1 mg/kg:CNS,PUL

    SAVEAB    Sammlung von Vergiftungsfaellen. 10 (1939),50.
4.    

ivn-rat LD50:6 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 8 (1958),539.
5.    

ipr-mus LD50:20 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 35 (3)(1972),114.
6.    

scu-mus LD50:25 mg/kg

    PHTXA6    Pharmacology and Toxicology. Translation of FATOAO. 20 (1957),521.
7.    

ivn-mus LD50:6 mg/kg

    EJMCA5    European Journal of Medicinal Chemistry. Chimie Therapeutique. 10 (1975),291.
8.    

scu-rbt LDLo:20 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 160 (1931),53.
9.    

ivn-rbt LDLo:6 mg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 160 (1931),53.
10.    

par-rbt LD50:33,500 µg/kg

    ARZNAD    Arzneimittel-

Tetracaine Safety Profile

A human poison by parenteral route with systemic effects including: muscle contractions, coma, and cyanosis. A poison experimentally by intravenous, parenteral, intratracheal, intraperitoneal, and subcutaneous routes. Human mutation data reported. A local anesthetic. See also ESTERS. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:Xn,Xi
Xi:Irritant
Xn:Harmful
Risk Statements
R22:Harmful if swallowed.
R40:Limited evidence of a carcinogenic effect.
R42/43:May cause sensitization by inhalation and skin contact .
R43:May cause sensitization by skin contact.
Safety Statements
S22:Do not breathe dust .
S36/37:Wear suitable protective clothing and gloves .
RIDADR:UN 2811
RTECS:DG4725000  

Tetracaine Specification

 Tetracaine , its CAS NO. is 94-24-6, the synonyms are 2-(Dimethylamino)ethyl p-(butylamino)benzoate ; 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove ; 2-Dimethylaminoethylesterkyselinyp-butylaminobenzoove ; 2-Dimethylaminoethylp-butylaminobenzoate ; 4-(Butylamino)-benzoicaci2-(dimethylamino)ethylester ; Amethocaine ; Anetain ; 2-(Dimethylamino)ethyl 4-(butylamino)benzoate . 

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