Once the compounds are synthesized, they are tested in biological assays to assess their effectiveness in inhibiting PRMT5 in real biological systems. This step is crucial to confirm the compounds' potential as drug candidates.
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5-(3,4-dimethoxybenzylidene)-2-(4-methylphenyl)-1,3-thiazol-4(5H)-one
6-Amino-2-phenethyl-2H-pyrazolo[3,4-d]pyrimidin-4(5H)-one
1-(2-O-acetyl-3,5-di-O-benzoyl-β-L-xylofuranosyl)-5-fluorouracil
Thiocarbonic acid O-[(2R,3R,4R,5S)-5-benzyloxymethyl-4-fluoromethyl-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl] ester O-phenyl ester
4'-CHLOROBIPHENYL-3-CARBALDEHYDE
