Syntheses and Biological Evaluations of 3'-Deoxy-3'-C-Branched-Chain-Substituted Nucleosides

DOI: 10.1021/jm00055a006

Source and publish data:

Journal of Medicinal Chemistry p. 353 - 362 (1993)

Update date:2022-07-30

Topics: Syntheses Nucleosides Biological evaluations Experimental

Authors:

Lin, Tai-Shun

Zhu, Ju-Liang

Dutschman, Ginger E.

Cheng, Yung-Chi

Prusoff, William H.

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Article abstract of DOI:10.1021/jm00055a006

Various 3'-deoxy-3'-C-(hydroxymethyl)-, 3'-deoxy-3'-C-(fluoromethyl)-, 3'-deoxy-3'-C-(azidomethyl)-, and 3'-deoxy-3'-C-(aminomethyl)-substituted nucleosides (total 12 compounds) have been synthesized and evaluated against L1210, P388, S-180, and CCRF-CEM

Full text of DOI:10.1021/jm00055a006

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