DIC (Diisopropylcarbodiimide)

A coupling reagent used in peptide synthesis.

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Solid-phase synthesis Yield Cleavage Mass spectrometry (MS) Solubility Deprotection HPLC (high-performance liquid chromatography) Protecting group Purification Peptide Synthesis Circular Dichroism (CD) Coupling Solid-Phase Peptide Synthesis (SPPS) Coupling Reaction Biological Activity Activation Receptor Binding Amino Acid Sequence Purity Peptide bond Resin Linker Aggregation Retention time Fmoc (Fluorenylmethyloxycarbonyl) TFA (Trifluoroacetic Acid) Lyophilization (Freeze-Drying) HOBt (Hydroxybenzotriazole) Fmoc chemistry Resin (Solid Support) Secondary Structure Side-chain protection

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