Fmoc chemistry

A common strategy in peptide synthesis using fluorenylmethyloxycarbonyl (Fmoc) protecting groups.

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Synthesis Solid-phase synthesis Yield Cleavage Mass spectrometry (MS) Solubility Deprotection HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Protecting group Analogues Purification Peptide Synthesis Circular Dichroism (CD) Structure-Activity Relationship (SAR) Solid-Phase Peptide Synthesis (SPPS) Coupling Reaction Biological Activity Receptor Binding Amino Acid Sequence Purity Peptide bond Resin Agonist Receptor binding assay Linker Aggregation Retention time TFA (Trifluoroacetic Acid) Lyophilization (Freeze-Drying) HOBt (Hydroxybenzotriazole) Resin (Solid Support) DIC (Diisopropylcarbodiimide) Secondary Structure

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