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Dinucleosides

Molecules composed of two nucleosides linked together, such as the dinucleoside phosphate.

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Articles of Dinucleosides

Synthesis of carbonate analogs of dinucleosides. 3'-Thymidinyl 5'-thymidinyl carbonate, 3'-thymidinyl 5'-(5-fluoro-2'-deoxyuridinyl) carbonate, and 3'-(5-fluoro-2'-deoxyuridinyl) 5'-thymidinyl carbonate.
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Oligonucleotide analogues with integrated bases and backbones: Part 26 - Synthesis, conformational analysis, and association of aminomethylene-linked self-complementary adenosine and uridine dinucleosides with enforced syn-conformation
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Synthesis Analog Mass spectrometry (MS) Protecting groups Deprotection HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) X-ray crystallography Stacking interactions Circular Dichroism (CD) Conformational Analysis Thermodynamic Stability Base Pairing Hydrophobicity Isosteric Replacement Experimental terms Carbonate Melting temperature (Tm) Phosphoramidite chemistry Molecular Dynamics (MD) Self-complementary Duplex formation Sugar pucker

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