Substituting a part of the mevinolin molecule with a bioisostere (a molecule with similar shape and properties) can improve the drug's characteristics. For example, replacing a functional group with another that has similar steric and electronic properties may enhance the drug's stability or interaction with its target.
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4(R)-(tert-butyldimethylsiloxy)-6(R)-<2-<8(S)-(benzyloxy)-1,2,6,7,8,8a(S)-hexahydro-2(S),6(R)-dimethyl-1(S)-naphthyl>ethyl>-2-<(tetrahydropyran-2-yl)oxy>-3,4,5,6-tetrahydro-2H-pyran
Glycine, N-[N-[(phenylmethoxy)carbonyl]thioglycyl]-, methyl ester
