Epothilones are a class of natural products that stabilize microtubules and inhibit tubulin polymerization. Some epothilone derivatives have been synthesized with a triazole ring, enhancing their bioactivity.
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N-(3-fluoro-4-methoxy-phenyl)-3,4,5-trimethoxy-thiobenzamide
3
Triethylamine
(4R,5S,6S)-7-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-2,2,4,6-tetramethyl-3-oxo-heptanal
1,4-Dioxaspiro[4.5]decane-8-carboxylic acid, 6,6-dimethyl-7-oxo-, phenylmethyl ester
