Researchers design and synthesize a range of pyrazole compounds, often with varying chemical structures or functional groups attached to the pyrazole ring. These compounds are typically designed to interact with the active site of the COX-2 enzyme, inhibiting its activity.
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3-(4-chlorophenyl)-1-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde
1-Methyl-5-(5-nitro-2-propoxyphenyl)-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
3-(3,4-dimethoxyphenyl)-1-(furan-2-yl)prop-2-en-1-one
C15H10BrClO2
5'-deoxy-5'-(4-nitrobenzamido)thymidine
Benzamide, N-(2-hydroxy-3-phenoxypropyl)-4-nitro-
dehydroandrographolide
C25H24BrNO2
Carbamic acid, [2-oxo-2-[(2-phenylethyl)amino]ethyl]-, phenylmethyl ester
(2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-bis(acetyloxy)-9-({(2R,3S)-3-(benzoylamino)-3-phenyl-2-[(triethylsilyl)oxy]propanoyl}oxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9, 10,11,12,12a,12bdodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
C20H14BrN3O5
N-(4-chloro-3-fluorophenyl)-2-(5-methoxy-1H-benzo[d]imidazol-2-ylthio)acetamide
4-(5-phenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide
AMINES
4-Dimethylaminopyridine
2-phenyl-6-(3-phenylpropyl)pyridine
2-amino-4-(4-fluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
2-((benzoyloxy)methyl)-5-(4,5-diamino-2-oxopyrimidin-1(2H)yl)tetrahydrofuran-3,4-diyl dibenzoate
1,7-bis(4-hydroxy-3-methoxyphenyl)-4-(2-(p-tolyl)hydrazono)hepta-1,6-diene-3,5-dione
C48H30F9NO3
7-methoxy-8-{6-[2-methoxy-4-[(E)-3-morpholino-3-oxo-1-propenyl]phenoxy]hexyloxy}-(11aS)-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one
2,6-Piperidinedione, 3-(4-aminophenyl)-3-methyl-
1-phenacyl-3-hydroxy-4-hydroxyiminomethyl-5-hydroxymethyl-2-methyl pyridinium bromide
tabun
PARAOXON
1-(3-Methoxymethyl-4-oxiranylmethoxy-phenyl)-ethanone
Fumaric acid
2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid 2-oxo-1,2-diphenyl-ethyl ester
N-[4-(imidazo[1,2-b]pyridazin-6-yloxy)phenyl]-N'-phenylurea
3-(4-bromo-2-fluorobenzylsulfonyl)-5-(4-isopropylthiazol-2-yl)-4-phenyl-4H-1,2,4-triazole
C27H36BN3O7
3-(benzylaminocarbonyl)-6,7-dimethoxy-1-methylquinolinium triflate
C84H60N16O16
Cyanuric chloride
5-(Dimethoxy-phosphoryl)-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3-carboxylic acid 2-cyano-ethyl ester
5-(1H-indol-3-yl)-3-(4-methylphenyl)-4,5-dihydroisoxazoline
1,4-Dioxaspiro[4.5]decane-8-carboxylic acid, 6,6-dimethyl-7-oxo-, phenylmethyl ester
3-(2-chloro-4-methyl-phenyl)-propionic acid
(E)-3-(4-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxy)-3-methoxyphenyl)acrylic acid
sodium piperidin-1-yldithiocarbamate
(R)-2-BENZYL-SUCCINIC ACID 1-BENZYL ESTER
Hexanoic acid, 5-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-6-oxo-, methyl ester, (5S)-
BIOTIN AMIDITE
(2S,2'R)-benzyl 2-[(3'-{[(tert-butoxy)carbonyl]amino}propionyl)oxy]-4-methylpentanoate
N-(4-(4-(2-aminoethylamino)-6-(3-methyl-1H-pyrazol-5-ylamino)pyrimidin-2-ylthio)phenyl)cyclopropanecarboxamide
(5'R)-3β-acetoxy-17β-[2-phenyl-4,5-dihydrooxazol-5-yl]androst-5-ene
(9H-fluoren-9-yl)methyl ((R)-1-(3-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)ureido)-2-methylpropyl)carbamate
4-[4-(4-fluoro-phenyl)-5-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonyl chloride
C50H57N5O13Si
C30H42N4O6
