The individual fragments are then connected or coupled to form the core structure of manoalide. This step is often challenging and requires careful planning.
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3-Hexen-1-ol, 4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (Z)-
(2S,3S,4S)-3-benzyloxy-2-methyl-4-[(4S,5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl]pentyl 4-methyl-1-benzenesulfonate
Fmoc-Tyr(Bzl)-Pro-Cl
tert-butyl(2-(2R,5R)-5-{[(tert-butyldimethylsilyloxy)methyl]tetrahydrofuran-2-yl}-ethoxy)diphenylsilane
<3R,4S,5S>-3-methoxy-5-<(p-methoxybenzyl)oxy>-6,6-dimethyl-4-(triethylsiloxy)-7-(trimethylsiloxy)-7-octenyl pivalate
