Fmoc-peptide acid chlorides in fragment coupling: Synthesis of β- casomorphin by 3+2 divergent approach

Article abstract of DOI:10.1080/00397919908085738

Fmoc-peptide acid chlorides are prepared and used as rapid and efficient coupling agents in fragment coupling. Thus the synthesis of the model tetrapeptide Leu-Ala-Gly-Val and β-casomorhin (Tyr-Pro-Phe-Pro-Gly) are accomplished by the (2+2) and (3+2) divergent approach respectively.

Full text of DOI:10.1080/00397919908085738

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Fmoc-Peptide Acid Chlorides in
Fragment Coupling: Synthesis
of β-Casomorphin by 3+2
Divergent Approach
V. V. Suresh Babu a , K. Gayathri b & H. N. Gopi a
a Department of Studies in Chemistry , Central
College Campus, Bangalore University , Bangalore,
560 001, India
b Department of Chemistry , Sri Aurebindo First
Grade College , Bangalore, 560 010, India
Published online: 17 Sep 2007.
To cite this article: V. V. Suresh Babu , K. Gayathri & H. N. Gopi (1999) Fmoc-
Peptide Acid Chlorides in Fragment Coupling: Synthesis of β-Casomorphin by
3+2 Divergent Approach, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 29:1, 79-91, DOI:
10.1080/00397919908085738
To link to this article: http://dx.doi.org/10.1080/00397919908085738
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