Some compounds may form covalent bonds with MAO-B, leading to irreversible inhibition. This means that the enzyme is permanently inactivated, and new enzyme molecules must be synthesized to restore its activity.
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2-methanesulfinyl-benzonitrile
1-(4-methoxyphenyl)-7-phenoxyheptane
2-Propenamide, N-(4-fluorophenyl)-
1-<4-(2-cyclopropylmethoxyethyl)phenoxy>-3-<1-p-(azidophenyl)-2-methyl-2-propylamine>-2-propanol
