Journal of Pharmaceutical Sciences p. 1117 - 1119 (1985)
Update date:2022-07-30
Topics: Synthesis Bromination Derivative Irreversible Inhibition β-Adrenergic receptors
Amlaiky
Leclerc
1-[4-(2-Cyclopropylmethoxyethyl)phenoxyl]-3-[1-p-(bromoacetamidophenyl)-2 -methyl-2-propylamine]-2-propanol (8), which is a derivatve of the β1-adrenergic agent betaxolol, was synthesized. Compound 8 showed less potent β-adrenergic blocking act
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