The selective inhibition of receptor tyrosine kinase c-Met indicates that PF-04254644 might be particularly useful in cancers and other diseases where c-Met signaling is a critical driver. Lessons learned here include the importance of targeting specific kinases involved in disease pathways.
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6-((6-(3,4-difluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-methyl)quinoline
