The fact that PF-04254644 is a selective inhibitor of c-Met receptor tyrosine kinase is a significant achievement. This suggests that it can be used as a tool compound in research and potentially as a therapeutic agent for conditions where c-Met is overactive, such as in certain cancers. The selectivity for c-Met may help minimize off-target effects.
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6-((6-(3,4-difluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-methyl)quinoline
