Minor groove binder

A molecule that binds to the minor groove of DNA, typically targeting specific base sequences.

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Solid-phase synthesis Mass spectrometry Antimicrobial activity Mass spectrometry (MS) IC50 Pyrrole Protecting groups Cytotoxicity binding affinity HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Circular Dichroism (CD) Docking Studies Antitumor Activity Structure-Activity Relationship (SAR) High-Throughput Screening (HTS) Library Synthesis DNA Binding Affinity DNA Binding Antibiotic Cell viability assay Netropsin Fluorescence assay N-Methylation HPLC purification Oligopeptide Synthetic Analogue

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