Journal of Medicinal Chemistry p. 33 - 38 (1981)
Update date:2022-08-02
Topics: Solid-phase synthesis Mass spectrometry Antimicrobial activity Pyrrole Protecting groups HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Circular Dichroism (CD) Structure-Activity Relationship (SAR) DNA Binding Affinity Antibiotic N-Methylation Minor groove binder HPLC purification Oligopeptide Synthetic Analogue
Gendler, Paul L.
Rapoport, Henry
The synthesis of an analogue of distamycin A, a pyrrolic oligopeptide possessing antiviral and antibiotic activity, is described in which each of the three pyrrole rings is fully methylated.This structural modification results in pyrrole rings which are e
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(1981)Doi:10.1021/jo0491408
(2004)Doi:10.1021/jo01278a020
(1967)Doi:10.1007/BF00950585
(1980)Doi:10.1021/ja01632a021
(1954)Doi:10.1007/BF00503664
(1981)
