Intramolecular reactions can be used to form the piperidine ring. For example, a molecule with appropriate functional groups can be induced to cyclize to form the piperidine ring.
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N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(1-methylpiperidin-4-yl)acetamide
9
3
(Z)-3-Amino-3-[1-(2-ethoxy-ethoxy)-cyclohexyl]-acrylic acid tert-butyl ester
(-)-(S)-3-vinylcyclohex-2-en-1-yl benzoate
(Z)-4-Methoxy-1-phenyl-2-trimethylsilanyl-but-2-en-1-one
