NEW SYNTHETIC METHODS FOR 4-AMINO-2(5H)-FURANONES

DOI: 10.1016/S0040-4039(00)94853-6

Source and publish data:

Tetrahedron Letters p. 2459 - 2462 (1985)

Update date:2022-07-29

Topics: Transition Metal-Catalyzed Reactions Multicomponent Reactions (MCRs) Ring-Closing Reactions Enzymatic Synthesis

Authors:

Hiyama, Tamejiro

Oishi, Haruhito

Saimoto, Hiroyuki

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Article abstract of DOI:10.1016/S0040-4039(00)94853-6

Two new efficient methods are disclosed for the synthesis of the title compounds: (1) base-promoted ring closure of 2-acyloxy alkanenitrile and (2) acid-mediated lactonization of t-butyl-4-alkoxy-3-amino-2-alkenoates.

Full text of DOI:10.1016/S0040-4039(00)94853-6

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