Some transition metal-catalyzed reactions, such as asymmetric hydrogenation or asymmetric Heck reactions, can be adapted for the synthesis of spiro compounds.
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(3R,7aS)-3-phenyl-7a-(3-phenylpropyl)-2,3,7,7a-tetrahydropyrrolo[2,1-b]oxazol-5-one
(Z)-3-Amino-3-[1-(2-ethoxy-ethoxy)-cyclohexyl]-acrylic acid tert-butyl ester
C29H41NO3
(S)-2-N,N-dibenzylamino-3-cyanopropanoic acid benzyl ester
