Scale-Up and Manufacturing

Develop scalable methods for synthesizing α-LNA for large-scale applications, if needed.

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Synthesis and evaluation of α-LNA
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Synthesis Solid-phase synthesis Characterization Deprotection Purification Structure-Activity Relationship (SAR) Analysis In vitro Testing In Vivo Testing Literature Review In Vivo Studies Lead Optimization Integration Monitoring and Control Toxicity Assessment Formulation Development Regulatory Approval Pharmacokinetic Studies Preclinical and Clinical Trials Pharmacokinetics and Pharmacodynamics Biological Activity Efficiency Enhancement Post-Market Surveillance Testing and Validation Target Identification Melting Temperature (Tm) Analysis Material Selection Light Absorption Environmental Impact

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