Correlate the structural modifications with the observed biological activities. Identify which structural features are critical for the observed effects. Discuss the potential mechanisms of action based on the SAR findings.
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10,12-Di-O-acetyl-iso-bilobalid
(2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol
