Based on the SAR analysis and other experimental data, iteratively design and synthesize new analogs with further modifications. Strive to identify the optimal structural features of the glucose moiety that provide the desired pharmacological profile.
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(2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol
(4-(2-hydroxyethoxy)phenyl)(6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)methanone
