Tetrahydroisoquinoline

A heterocyclic compound containing a benzene ring fused to a nitrogen-containing five-membered ring.

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Total Synthesis of Tetrahydroisoquinoline-Based Bioactive Natural Products Laudanosine, Romneine, Glaucine, Dicentrine, and Their Unnatural Analogues Isolaudanosine and Isoromneine
Related Chemicals
- 1-(3',4'-dimethoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
Diprotonative stabilization of ring-opened carbocationic intermediates: conversion of tetrahydroisoquinoline to triarylmethanes
Related Chemicals
- 1-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-isoquinoline
Iodine as a mild, efficient, and cost-effective reagent for the synthesis of cis-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acids
Related Chemicals
- 4-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-1-oxo-2,3-diphenyl-, (3R,4S)-rel-
Identification of (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1- piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3- isoquinolinecarboxamide as a novel potent and selective opioid κ receptor antagonist
Related Chemicals
- (3R)-4-(3-isopropoxyphenyl)-1,3,4-triMethylpiperidine
4-Substituted-1,2,3,4-tetrahydro-3,3-dimethylisoquinolines. II. (1)
Related Chemicals
- α-<1-<(3-methoxyphenylmethyl)amino>-1-methylethyl>benzenemethanol
Selective and potent β₂-adrenoceptor agents within the tetrahydroisoquinoline class: Effect of methyl substitution at the benzylic carbon of the 1-(3,4,5-trimethoxybenzyl) group of trimetoquinol
Related Chemicals
- 2-(3,4,5-trimethoxyphenyl)propionic acid

Synthesis Oxidation Conversion Pharmacological evaluation Regioselectivity Yield NMR spectroscopy Catalyst Selectivity Nucleophile Electrophile Solvent Stereochemistry Chromatography Recrystallization Total synthesis Potency Reagent Stirring Cyclization Isoquinoline Natural products TLC (thin-layer chromatography) NMR (nuclear magnetic resonance) Purification In vitro Testing In Vivo Testing Reaction Mechanism Structure-Activity Relationship (SAR) Chirality Temperature Control Substituent Bioactive Triarylmethanes Receptor binding assay Antagonist activity Hydroxyphenyl Carboxylic acid (-COOH) IR Spectroscopy (Infrared Spectroscopy)

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