Selective and potent β2-adrenoceptor agents within the tetrahydroisoquinoline class: Effect of methyl substitution at the benzylic carbon of the 1-(3,4,5-trimethoxybenzyl) group of trimetoquinol

DOI: 10.1021/jm00140a011

Source and publish data:

Journal of Medicinal Chemistry p. 970 - 974 (1981)

Update date:2022-08-04

Topics: Tetrahydroisoquinoline

Authors:

Sober Sober

Chang Chang

Fowble Fowble

Mukhopadhyay

Feller Feller

Miller Miller

Fairchild

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00140a011

A systematic series of methyl (2 and 3) and dimethyl (4) analogues of trimetoquinol (1) were synthesized and evaluated for their β₁ (atria) and β₂ (trachea) adrenoceptor activities. Structural assignments for the erythro (2) and the

Full text of DOI:10.1021/jm00140a011

Products guided by the article

Product name:N-<3,4-bis(benzyloxy)phenethyl>-2-methyl-2-(3,4,5-trimethoxyphenyl)propionamide

Cas No:78131-09-6

R&D Labs maybe for 78131-09-6

Zhengzhou Institute of Chiral Pharmer Research Co., Ltd.

Contact:86-371-55219111

Address:15 Floor, 2 Building, Central China Technovalley, Zhongyuan West Road
SHANGHAI GILEADER ADVANCE MATERIAL TECHNOLOGY CO.,LTD

website:http://www.tanguitech.com/contact.asp

Contact:+86-021-58692556

Address:No.6 Building,No. 668 Hengan RD Pudong,Shanghai
Hebei Kangtai Pharmaceutical Co.,Ltd

Contact:+86-0317-3512963

Address:Wugang Road,Mengcun of Cangzhou City,Hebei Province ,China
Xinjiang Fufeng Biotechnologies Co., Ltd.

Contact:+86-539-7287111

Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
Jinan Finer Chemical Co., Ltd

website:https://www.finerchem.com

Contact:+86-531-88989536

Address:New Material Industrial Park, Jinan City, China

Relevant to this article

Preparation, characterization and electrochemical studies of 1,1′-bis(diphenylphosphino)ferrocene (dppf) derivatives. Crystal structure of [dppfCo(NO)₂] [SbF₆]

Doi:10.1016/S0020-1693(97)05527-8
(1997)
Enantiopure azetidine-2-carboxamides as organocatalysts for direct asymmetric aldol reactions in aqueous and organic media

Doi:10.1016/j.tet.2013.12.081
(2014)
Synthesis of cyclic α-hydrazino acid derivatives via N-acylhydrazonium ions

Doi:10.1016/S0040-4020(01)96267-2
(1993)
Ionic liquid/HCl catalyzed synthesis of 4-(trifluoromethyl)-2(1H)- pyrimidinones

Doi:10.1007/s00706-013-1126-0
(2014)
3-Trifluoromethylthiophens from hexafluoroacetone

Doi:10.1016/0022-1139(93)02906-U
(1994)
7-Fluoro-4-chromone-3-sulfur compounds

Doi:10.1002/ardp.19943270413
(1994)

Article Doi