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Triethylene glycol monoethyl ether

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Name

Triethylene glycol monoethyl ether

EINECS 203-978-9
CAS No. 112-50-5 Density 1.006 g/cm3
PSA 47.92000 LogP 0.04840
Solubility 1.02g/L at 20℃ Melting Point -19°C(lit.)
Formula C8H18O4 Boiling Point 255.999 °C at 760 mmHg
Molecular Weight 178.229 Flash Point 106.443 °C
Transport Information N/A Appearance Odorless colorless liquid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 112-50-5 (Triethylene glycol monoethyl ether) Hazard Symbols N/A
Synonyms

Triethylene glycol monoethyl ether;Ethyltriglycol;2-[2-(2-ethoxyethoxy)ethoxy]ethanol;Tri(ethylene glycol) monoethyl ether;

Article Data 9

Triethylene glycol monoethyl ether Synthetic route

136399-06-9

2-(2-(2-(2-iodoethoxy)ethoxy)ethoxy)ethanol

112-50-5

monoethyl ether of triethylene glycol

Conditions
ConditionsYield
With tri(2-furyl)germane; 2,2’-azobis(4-methoxy-2,4-dimethyl)valeronitrile In water at 80℃; for 1h;97%
75-03-6

ethyl iodide

112-27-6

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

112-50-5

monoethyl ether of triethylene glycol

Conditions
ConditionsYield
With potassium hydroxide In tetrahydrofuran for 4h; Ambient temperature;60%
75-21-8

oxirane

64-17-5

ethanol

112-50-5

monoethyl ether of triethylene glycol

Conditions
ConditionsYield
With sulfuric acid at 80 - 100℃;
75-21-8

oxirane

111-90-0

ethoxyethoxyethanol

112-50-5

monoethyl ether of triethylene glycol

Conditions
ConditionsYield
With ethanolamine at 50 - 60℃;
75-21-8

oxirane

111-90-0

ethoxyethoxyethanol

A

112-50-5

monoethyl ether of triethylene glycol

B

5650-20-4

3,6,9,12-tetraoxatetradecan-1-ol

Conditions
ConditionsYield
With ethanolamine at 50 - 60℃;
75-21-8

oxirane

111-90-0

ethoxyethoxyethanol

141-43-5

ethanolamine

A

112-50-5

monoethyl ether of triethylene glycol

B

5650-20-4

3,6,9,12-tetraoxatetradecan-1-ol

Conditions
ConditionsYield
at 50 - 63℃;
111-90-0

ethoxyethoxyethanol

107-07-3

2-chloro-ethanol

112-50-5

monoethyl ether of triethylene glycol

Conditions
ConditionsYield
at 70 - 80℃; reagiert das Natriumsalz;
74-96-4

ethyl bromide

112-27-6

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

112-50-5

monoethyl ether of triethylene glycol

Conditions
ConditionsYield
(i) Na, (ii) /BRN= 1209224/; Multistep reaction;
107-07-3

2-chloro-ethanol

sodium salts of diethylene glycol-monoethyl ether

sodium salts of diethylene glycol-monoethyl ether

112-50-5

monoethyl ether of triethylene glycol

Conditions
ConditionsYield
at 70 - 80℃;
75-21-8

oxirane

64-17-5

ethanol

A

112-50-5

monoethyl ether of triethylene glycol

B

2-ethoxy-ethanol, O-ethyl-diethylene glycol

2-ethoxy-ethanol, O-ethyl-diethylene glycol

Conditions
ConditionsYield
With sodium ethanolate

Triethylene glycol monoethyl ether Chemical Properties

Chemical Name: Triethylene glycol monoethyl ether
IUPAC NAME: 2-[2-(2-Ethoxyethoxy)ethoxy]ethanol
CAS No.: 112-50-5
EINECS: 203-978-9
RTECS: KK8950000
Molecular Formula: C8H18O4
Molecular Weight: 178.23 g/mol
Density: 1.005 g/cm3 
Flash Point: 106.4 °C
Boiling Point: 256 °C at 760 mmHg 
Following is the structure of Ethoxytriglycol (112-50-5):


Product Categories about Ethoxytriglycol (112-50-5) are Ethylene Glycols & Monofunctional Ethylene Glycols ; Monofunctional Ethylene Glycols
The chemical synonymous of Ethoxytriglycol (112-50-5) are Triglycol monoethyl ether ; Triethylene glycol monoethyl ether ; Triethylene Glycol ethyl ether ; 2-[2-(2-Ethoxyethoxy)ethoxy]ethanol ; Ethyltriglycol ; Ethoxytriglycol ; Ethoxytriethylene glycol ; 2-(2-(2-Ethoxyethoxy)ethoxy)-ethano

Triethylene glycol monoethyl ether Uses

 Ethoxytriglycol (112-50-5) is mainly used for coatings, inks, dyes, resins, nitrocellulose of high boiling point solvent.

Triethylene glycol monoethyl ether Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 3070mg/kg (3070mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982.
mouse LD50 oral 5799mg/kg (5799mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982.
rabbit LD50 skin 8mL/kg (8mL/kg)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat LD50 oral 7750mg/kg (7750mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 47(5), Pg. 84, 1982.

Triethylene glycol monoethyl ether Consensus Reports

Reported in EPA TSCA Inventory. Glycol ether compounds are on the Community Right-To-Know List.

Triethylene glycol monoethyl ether Safety Profile

Mildly toxic by ingestion and skin contact. An eye irritant. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS.

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