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Basic Information
| CAS No.: | 109-07-9 |
|---|---|
| Name: | 2-Methylpiperazine |
| Article Data: | 34 |
| Molecular Structure: | |
|
|
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| Formula: | C5H12N2 |
| Molecular Weight: | 100.164 |
| Synonyms: | Piperazine,2-methyl-, (?à)-;(?à)-2-Methylpiperazine;2-Methylpiperazine;NSC 5277; |
| EINECS: | 203-644-2 |
| Density: | 0.845 g/cm3 |
| Melting Point: | 61-63 °C(lit.) |
| Boiling Point: | 153.2 °C at 760 mmHg |
| Flash Point: | 45.1 °C |
| Solubility: | 78 g/100 mL (25 °C) in water |
| Appearance: | white to yellow crystalline powder and chunks |
| Hazard Symbols: |
 F, Xi
|
| Risk Codes: | 11-36/37/38 |
| Safety: | 16-26-36/37/39-36 |
| Transport Information: | UN 1325 4.1/PG 2 |
| PSA: | 24.06000 |
| LogP: | 0.22530 |
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2-Methylpiperazine
Chemistry
MF: C5H12N2 
MW: 100.16
mp of 2-METHYLPIPERAZINE (109-07-9): 61-63 °C(lit.)
bp of 2-METHYLPIPERAZINE (109-07-9): 155 °C 763 mm Hg(lit.)
density: 0.817 g/cm3
Fp of 2-METHYLPIPERAZINE (109-07-9): 149 °F
storage temp.: Flammables area
Water Solubility: 78 g/100 mL (25 oC)
PHYSICAL STATE: white crystal
MW: 100.16
mp of 2-METHYLPIPERAZINE (109-07-9): 61-63 °C(lit.)
bp of 2-METHYLPIPERAZINE (109-07-9): 155 °C 763 mm Hg(lit.)
density: 0.817 g/cm3
Fp of 2-METHYLPIPERAZINE (109-07-9): 149 °F
storage temp.: Flammables area
Water Solubility: 78 g/100 mL (25 oC)
PHYSICAL STATE: white crystal
Uses
2-METHYLPIPERAZINE (109-07-9) is used as pharmaceutical intermediates, synthetic Lomefloxacin raw materials. It is used in the synthesis of drugs like quinolone class antibiotics, agrochemicals and other chemical compounds.
Toxicity Data With Reference
| 1. | orl-rat LD50:2030 mg/kg | JACTDZ Journal of the American College of Toxicology. 1 (1990),58. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Hazard Codes: F,Xi (Highly Flammable; Irritant)
Risk Statements: 11-36/37/38 (Highly Flammable; Irritating to eyes, respiratory system and skin)
Safety Statements: 16-26-36/37/39-36 (Keep away from sources of ignition - No smoking; In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear suitable protective clothing, gloves and eye/face protection; Wear suitable protective clothing)
RIDADR: UN 1325 4.1/PG 2
WGK Germany: 2
RTECS: TM1225020
F: 10 (Keep under argon)
HazardClass: 4.1
PackingGroup: III
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.
Risk Statements: 11-36/37/38 (Highly Flammable; Irritating to eyes, respiratory system and skin)
Safety Statements: 16-26-36/37/39-36 (Keep away from sources of ignition - No smoking; In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear suitable protective clothing, gloves and eye/face protection; Wear suitable protective clothing)
RIDADR: UN 1325 4.1/PG 2
WGK Germany: 2
RTECS: TM1225020
F: 10 (Keep under argon)
HazardClass: 4.1
PackingGroup: III
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.
Standards and Recommendations
PURITY: 99.0% min
WATER: 0.5% max
INDIVIDUAL IMPURITY: 0.5% max
WATER: 0.5% max
INDIVIDUAL IMPURITY: 0.5% max
Specification
Storage: Store away from water/moisture. Do not store together with oxidizing and acidic materials. Keep container tightly sealed. Store in cool, dry conditions in well sealed containers.