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144-68-3

Basic Information
CAS No.: 144-68-3
Name: Zeaxanthin
Article Data: 50
Molecular Structure:
Molecular Structure of 144-68-3 (Zeaxanthin)
Formula: C40H56O2
Molecular Weight: 568.883
Synonyms: all-trans-Anchovyxanthin;all-trans-Zeaxanthin;Zeaxanthin(7CI);b-Carotene-3,3'-diol, (3R,3'R)-all-trans- (6CI,8CI);(3R,3'R)-Zeaxanthin;Anchovyxanthin;Anchovyxanthin, all-trans-;Xanthophyll 3;ZeaGold;Zeaxanthin,all-trans-;Zeaxanthol;
EINECS: 205-636-4
Density: 1.008 g/cm3
Melting Point: 203-205 °C
Boiling Point: 711.4 °C at 760 mmHg
Flash Point: 273.4 °C
Solubility: insoluble in water
Appearance: yellow crystalline solid
PSA: 40.46000
LogP: 10.54740
Synthetic route
7481-64-3

all-trans lutein

144-68-3

zeaxanthin

Conditions
ConditionsYield
With ethanol; sodium ethanolate; benzene at 100 - 110℃;
14656-56-5, 26543-85-1

3,3'-di-keto-β-carotene

555-31-7

aluminum isopropoxide

67-63-0

isopropyl alcohol

71-43-2

benzene

144-68-3

zeaxanthin

15486-31-4

(2E,4E,6E,8E,10E,12E,14E)-15-(4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-4,9,13-trimethylpentadeca-2,4,6,8,10,12,14-heptaenal

<3-(4-hydroxy-2,2,6-trimethylcyclohexenyl)-1-methyl-2-propen-1-yl>triphenylphosphonium bromide

144-68-3

zeaxanthin

Conditions
ConditionsYield
With potassium hydroxide In isopropyl alcohol at 20℃; for 3h;8.5 mg

zeaxanthin radical cation

144-68-3

zeaxanthin

Conditions
ConditionsYield
With TX-100 In water Rate constant; Irradiation;
116-30-3

4',5'-didehydro-4,5'-retro-β,β-carotene-3,3'-dione

A

144-68-3

zeaxanthin

B

127-40-2

lutein

C

89673-72-3

(3R,3'S,6'R)-lutein

Conditions
ConditionsYield
With tellurium; sodium tetrahydroborate In carbon disulfide; ethanol at 40℃; for 0.333333h; Title compound not separated from byproducts;A 24 % Chromat.
B 44 % Chromat.
C 31 % Chromat.
With tellurium; sodium tetrahydroborate In carbon disulfide; ethanol at 40℃; for 0.333333h;A 24 % Chromat.
B 44 % Chromat.
C 31 % Chromat.
502-65-8

lycopene

zeaxanthin radical cation

A

144-68-3

zeaxanthin

B

lycopene radical cation

Conditions
ConditionsYield
In benzene Rate constant; pulse radiolysis;
all-trans-β-carotenedione-(3,3')

all-trans-β-carotenedione-(3,3')

144-68-3

zeaxanthin

Conditions
ConditionsYield
With aluminum isopropoxide; isopropyl alcohol; benzene
53163-53-4

(E)-4,9-dimethyl-2,4,6,8,10-dodecapentaene-1,12-dial

4-triphenylphosphoranylidene-pent-2t(?)-enoic acid methyl ester

4-triphenylphosphoranylidene-pent-2t(?)-enoic acid methyl ester

144-68-3

zeaxanthin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C
2: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
32469-38-8

4-(1,4-dihydroxy-2,2,6-trimethylcyclohexyl)-3-butyn-2-ol

144-68-3

zeaxanthin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 3.5 g / lithium aluminium hydride / tetrahydrofuran / 3 h / Heating
2: 2.21 g / CHCl3 / 18 h / 20 °C
3: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C
4: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 3.5 g / lithium aluminium hydride / tetrahydrofuran / 3 h / Heating
2: 2.21 g / CHCl3 / 18 h / 20 °C
3: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
53342-69-1

4-(4-hydroxy-2,2,6-trimethylcyclohexylidene)-3-buten-2-ol

144-68-3

zeaxanthin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 2.21 g / CHCl3 / 18 h / 20 °C
2: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C
3: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 2.21 g / CHCl3 / 18 h / 20 °C
2: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C
View Scheme
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7542-45-2
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  • Zeaxanthin	cas144-68-3  	C40H56O2

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    144-68-3

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    144-68-3

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Chemistry

IUPAC Name: (1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol   
Synonyms of Zeaxanthin (CAS NO.144-68-3): 3R 3'R Zeaxanthin ; (3R,3'R)-beta,beta-Carotene-3,3'-diol
CAS NO: 144-68-3
Molecular Formula: C40H56O2
Molecular Weight: 568.88
Molecular Structure:
EINECS: 205-636-4 
H bond acceptors: 2
H bond donors: 2
Freely Rotating Bonds: 12
Polar Surface Area: 18.46 Å2
Index of Refraction: 1.585
Molar Refractivity: 189.11 cm3
Molar Volume: 564.1 cm3
Surface Tension: 41.2 dyne/cm
Density: 1.008 g/cm3
Flash Point: 273.4 °C
Enthalpy of Vaporization: 118.87 kJ/mol
Boiling Point: 711.4 °C at 760 mmHg
Vapour Pressure: 2.19E-23 mmHg at 25°C 
Melting Point: 203-205°C
Storage temp: -20°C
Appearance: Yellow Crystalline Solid
Product Categories of Zeaxanthin (CAS NO.144-68-3): Carotenoids;Intermediates & Fine Chemicals;Pharmaceuticals

Uses

 Zeaxanthin (CAS NO.144-68-3) is used as a food additive, zeaxanthin is a food dye with E number E161h.

Safety Profile

 F: 3-8-10

Specification

Natural occurrence of Zeaxanthin (CAS NO.144-68-3): 
 Zeaxanthin is one of the most common carotenoid alcohols found in nature. It is the pigment that gives paprika (made from bell peppers), corn, saffron, and many other plants their characteristic color and Zeaxanthin breaks down to form picrocrocin and safranal, which are responsible for the taste and aroma of saffron.

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