CAS No.52-68-6,Chlorophos Suppliers,MSDS download

Products Categories

Pharmaceutical (41)
Others (21)
Agrochemicals (18)
Organic Chemicals (15)
Reagent (2)
Materials (1)
Plant Extract (1)

Basic Information

Molecular Structure:
CAS No.:	52-68-6
Name:	Chlorophos
Article Data:	25

Formula:	C₄H₈Cl₃O₄P
Molecular Weight:	257.438
Synonyms:	O, O-Dimethyl- (2,2,2-trichlor-1-hydroxy-aethyl)phosphonat;(1S)-2,2,2-trichloro-1-dimethoxyphosphoryl-ethanol;Dipterax;2,2,2-trichloro-1-dimethoxyphosphoryl-ethanol;Phosphonic acid, (2,2, 2-trichloro-1-hydroxyethyl)-, dimethyl ester;Proxol;Dipterex;Clorofos;Bayer L 1359;Trichlorofon (TN);Masoten;Phosphonic acid,(2,2,2-trichloro-1-hydroxyethyl)-,dimethyl ester;Agroforotox;Anthon;Foschlor R;Chlorophosciclosom;O,O-Dimethyl (2,2, 2-trichlorohydroxyethyl)phosphonate;Foschlor R-50;Trichlorphon FN;Briton;(1R)-2,2,2-trichloro-1-dimethoxyphosphorylethanolate;Satox 20WSC;Dyvon;(1-Hydroxy-2,2,2-trichloroethyl)phosphonic acid, dimethyl ester;Khloroftalm;O,O-Dimethyl (1-hydroxy-2,2, 2-trichloroethyl)phosphate;Aerol 1 (pesticide);(2,2, 2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester;Chloroxyphos;NCI-C54831;Phosphonic acid,(2,2,2-trichloro-1-hydroxy- ethyl)-,dimethyl ester;Onefon;BAY 15922;Trichlorphon;Volfartol;Metrifonate;Phosphonic acid, (1-hydroxy-2,2, 2-trichloroethyl)-, dimethyl ester;Votexit;Trichlorophone;O, O-Dimethyl- (1-hydroxy-2,2,2-trichlorathyl)-phosphat;Dyrex;Dimetox;Chlorophthalm;(1R)-2,2,2-trichloro-1-dimethoxyphosphoryl-ethanol;Dipterex 50;Dimethyl (2,2, 2-trichloro-1-hydroxyethyl)phosphonate;Metrifonate (USP);DEP (pesticide);(2,2,2-Trichloro-1-hydroxy)phosphonic acid, dimethyl ester;Fliegenteller;Azoxystrobi;TRICHLOPHON;Ritsifon;Ricifon;Chloroftalm;Foschlorem;O,O-Dimethyl (1-oxy-2,2, 2-trichloroethyl)phosphonate;Forotox;1-Hydroxy-2,2, 2-trichloro-ethyle phosphonate de dimethyle;Metriphonate;[(2,2, 2-Trichloro-1-hydroxyethyl) dimethylphosphonate];Diptevur;Danex;Trinex;Methyl chlorophos;Flibol E;Dylox;(2,2, 2-Trichloro-1-hydroxyethyl)phosphonate, dimethyl ester;Bovinox;O,O-Dimethyl- (1-hydroxy-2,2, 2-trichloraethyl)phosphosaeure ester;Loisol;Cekufon;Trichlorophon;Bilarcil;
EINECS:	200-149-3
Density:	1.574 g/cm³
Melting Point:	77-81 °C
Boiling Point:	269.3 °C at 760 mmHg
Flash Point:	116.7 °C
Solubility:	Slightly soluble in water
Appearance:	white crystals or powder
Hazard Symbols:	Xn, N
Risk Codes:	22-43-50/53
Safety:	24-37-60-61-2
Transport Information:	UN 3077 9/PG 3
PSA:	65.57000
LogP:	2.16090

Synthetic route

: 96-36-6, 868-85-9
methyl phosphite

: 75-87-6
chloral

: 52-68-6
trichlorfon

Conditions

Conditions	Yield
at 34℃; Rate constant;

: 186581-53-3, 908094-01-9
diazomethane

: 684-31-1
(2,2,2-trichloro-1-hydroxy-ethyl)-phosphonic acid monomethyl ester

: 52-68-6
trichlorfon

: 302-17-0
chloral hydrate

: 121-45-9
phosphorous acid trimethyl ester

A: 62-73-7
Dichlorvos

B: 52-68-6
trichlorfon

Conditions

Conditions	Yield
In hexane for 1h; Product distribution; Mechanism;
In hexane for 1h;

...Expand

: 302-17-0
chloral hydrate

: 121-45-9
phosphorous acid trimethyl ester

A: 62-73-7
Dichlorvos

B: 52-68-6
trichlorfon

C: 13445-62-0
dichlorovinylmethyl phosphoric acid

Conditions

Conditions	Yield
In hexane for 10h; Heating;

...Expand

: 302-17-0
chloral hydrate

: 868-85-9
Dimethyl phosphite

: 52-68-6
trichlorfon

Conditions

Conditions	Yield
With aluminum oxide for 0.1h; microwave irradiation;	74 % Spectr.

: 75-87-6
chloral

: 868-85-9
Dimethyl phosphite

: 52-68-6
trichlorfon

Conditions

Conditions	Yield
With aluminum oxide; potassium fluoride at 20℃; for 0.5h;
With aluminum oxide; potassium fluoride
With aluminum oxide; potassium fluoride
With aluminum oxide; potassium fluoride

: 302-17-0
chloral hydrate

: 121-45-9
phosphorous acid trimethyl ester

A: 67-56-1
methanol

B: 52-68-6
trichlorfon

Conditions

Conditions	Yield
Abramov reaction;

...Expand

: 52-68-6
trichlorfon

: 826990-47-0
2-(3-chloro-4-fluorophenoxy)acetyl chloride

: 866145-51-9
O,O-dimethyl 1-(3-chloro-4-fluorophenoxyacetoxy)-2,2,2-trichloroethylphosphonate

Conditions

Conditions	Yield
With triethylamine In chloroform at 2 - 20℃;	80%

: 3739-94-4
2,6-Pyridinedicarbonyl dichloride

: 52-68-6
trichlorfon

: 1208256-21-6
O,O-dimethyl-2,6-pyridinyldi(formyloxy-trichloromethyl-methylphosphonate)

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20 - 40℃; for 5h;	73%

: 52-68-6
trichlorfon

: 826990-46-9
2-(2-chloro-4-fluorophenoxy)acetyl chloride

: O,O-dimethyl (2-chloro-4-fluorophenoxyacetoxy)(trichloromethyl)methylphosphonate

Conditions

Conditions	Yield
With triethylamine In chloroform at 20℃; for 2h;	72.5%

Raw Materials

684-31-1

96-36-6

302-17-0

121-45-9

75-87-6

868-85-9

Downstream Products

76-05-1

375-22-4

756-09-2

62-73-7

Total:84 Page 1 of 3 1 2 3 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 52-68-6

Chemistry

Product Name: Trichlorfon (CAS NO.52-68-6)

Molecular Formula: C₄H₈Cl₃O₄P
Molecular Weight: 257.44g/mol
Mol File: 52-68-6.mol
Einecs: 257.44
Appearance: White crystals or powder
Melting Point: 77-81 °C
Boiling point: 269.3 °C at 760 mmHg
Flash Point: 116.7 °C
Density: 1.574 g/cm³
Water Solubility: Slightly soluble. 1-5 g/100 mL at 21 ºC
Surface Tension: 46.6 dyne/cm
Enthalpy of Vaporization: 58.92 kJ/mol
Vapour Pressure: 0.00097 mmHg at 25°C
XLogP3-AA: 0.5
H-Bond Donor: 1
H-Bond Acceptor: 4
Structure Descriptors of Trichlorfon (CAS NO.52-68-6):
IUPAC Name: 2,2,2-trichloro-1-dimethoxyphosphorylethanol
Canonical SMILES: COP(=O)(C(C(Cl)(Cl)Cl)O)OC
InChI: InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3
InChIKey: NFACJZMKEDPNKN-UHFFFAOYSA-N
Product Categories: INSECTICIDE; Bases & Related Reagents; Carbohydrates & Derivatives; Isotope Labeled Compounds; Nucleotides; Phosphorylating and Phosphitylating Agents

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	37mg/kg (37mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat	LD50	oral	97mg/kg (97mg/kg)		"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 60, 1982.
cat	LD50	unreported	98mg/kg (98mg/kg)	LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	Russian Pharmacology and Toxicology Vol. 50, Pg. 61, 1987.
chicken	LD50	oral	75mg/kg (75mg/kg)		Environmental Quality and Safety. Vol. 3, Pg. 173, 1974.
chicken	LD50	subcutaneous	125mg/kg (125mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)	Biochemical Pharmacology. Vol. 12, Pg. 1377, 1963.
dog	LD50	intravenous	150mg/kg (150mg/kg)	CARDIAC: OTHER CHANGES LIVER: OTHER CHANGES BLOOD: HEMORRHAGE	Archives of Toxicology. Vol. 41, Pg. 3, 1978.
dog	LD50	oral	400mg/kg (400mg/kg)	CARDIAC: OTHER CHANGES LIVER: OTHER CHANGES BLOOD: HEMORRHAGE	Archives of Toxicology. Vol. 41, Pg. 3, 1978.
dog	LD50	subcutaneous	269mg/kg (269mg/kg)	BEHAVIORAL: TREMOR GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: OTHER CHANGES	Revista do Centro de Ciencias Rurais Vol. 7(1), Pg. 23, 1977.
guinea pig	LD50	intraperitoneal	300mg/kg (300mg/kg)		AMA Archives of Industrial Health. Vol. 11, Pg. 53, 1955.
guinea pig	LDLo	oral	420mg/kg (420mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Bulletin of the University of Miami School of Medicine and Jackson Memorial Hospital. Vol. 9, Pg. 7, 1955.
hamster	LD50	intraperitoneal	1gm/kg (1000mg/kg)		Archives of Toxicology. Vol. 58, Pg. 152, 1986.
human	TCLo	inhalation	1710ug/m3/90D (1.71mg/m3)		British Journal of Industrial Medicine. Vol. 43, Pg. 414, 1986.
mammal (species unspecified)	LD50	skin	> 2800mg/kg (2800mg/kg)		Archives of Toxicology. Vol. 41, Pg. 3, 1978.
mammal (species unspecified)	LD50	unreported	295mg/kg (295mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(8), Pg. 101, 1973.
monkey	LD	oral	> 1gm/kg (1000mg/kg)	SPINAL CORD: OTHER DEGENERATIVE CHANGES MUSCULOSKELETAL: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES	Journal of UOEH Vol. 5(Suppl), Pg. 125, 1983.
mouse	LD50	intraperitoneal	196mg/kg (196mg/kg)		Toxicology and Applied Pharmacology. Vol. 2, Pg. 495, 1960.
mouse	LD50	intravenous	290mg/kg (290mg/kg)	CARDIAC: OTHER CHANGES LIVER: OTHER CHANGES BLOOD: HEMORRHAGE	Archives of Toxicology. Vol. 41, Pg. 3, 1978.
mouse	LD50	oral	300mg/kg (300mg/kg)		Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 26, 1978.
mouse	LD50	skin	1710mg/kg (1710mg/kg)		Yakkyoku. Pharmacy. Vol. 37, Pg. 597, 1986.
mouse	LD50	subcutaneous	267mg/kg (267mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
mouse	LD50	unreported	445mg/kg (445mg/kg)		Pharmaceutical Chemistry Journal Vol. 3, Pg. 508, 1969.
quail	LD50	oral	73110ug/kg (73.11mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Hokkaidoritsu Eisei Kenkyushoho. Report of the Hokkaido Institute of Public Health. Vol. 24, Pg. 35, 1974.
rabbit	LD	skin	> 1500mg/kg (1500mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, IRRITATIVE: AFTER SYSTEMIC EXPOSURE"	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 8(10), Pg. 54, 1964.
rabbit	LD50	intraperitoneal	60mg/kg (60mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	American Journal of Ophthalmology. Vol. 53, Pg. 512, 1962.
rabbit	LD50	oral	160mg/kg (160mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
rabbit	LDLo	intramuscular	500mg/kg (500mg/kg)	VASCULAR: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BLOOD: HEMORRHAGE	Medycyna Weterynaryjna. Veterinary Medicine. Vol. 35, Pg. 479, 1979.
rat	LC50	inhalation	1300mg/m3 (1300mg/m3)		Archiv fuer Geschwulstforschung. Vol. 48, Pg. 112, 1978.
rat	LD50	intramuscular	395mg/kg (395mg/kg)	CARDIAC: OTHER CHANGES LIVER: OTHER CHANGES BLOOD: HEMORRHAGE	Archives of Toxicology. Vol. 41, Pg. 3, 1978.
rat	LD50	intraperitoneal	160mg/kg (160mg/kg)		Advances in Pest Control Research. Vol. 4, Pg. 117, 1961.
rat	LD50	oral	450mg/kg (450mg/kg)		United States Patent Document. Vol. #5006545,
rat	LD50	skin	2gm/kg (2000mg/kg)		Archiv fuer Geschwulstforschung. Vol. 48, Pg. 112, 1978.
rat	LD50	subcutaneous	400mg/kg (400mg/kg)		Journal of Economic Entomology. Vol. 50, Pg. 356, 1957.
rat	LD50	unreported	550mg/kg (550mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(6), Pg. 21, 1982.
women	TDLo	oral	1mL/kg (1mL/kg)	AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: COMA	Journal of UOEH Vol. 5(Suppl), Pg. 125, 1983.
women	TDLo	oral	1200uL/kg (1.2mL/kg)	SPINAL CORD: OTHER DEGENERATIVE CHANGES AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC BEHAVIORAL: COMA	Journal of UOEH Vol. 5(Suppl), Pg. 125, 1983.
women	TDLo	oral	1364uL/kg (1.364mL/kg)	AUTONOMIC NERVOUS SYSTEM: GAGLION BLOCK BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SLEEP	Rinsho Shinkeigaku. Clinical Neurology. Vol. 21, Pg. 993, 1981.
women	TDLo	oral	240mg/kg (240mg/kg)	SPINAL CORD: OTHER DEGENERATIVE CHANGES PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: COMA	Journal of UOEH Vol. 5(Suppl), Pg. 125, 1983.

Safety Profile

Safety Information of Trichlorfon (CAS NO.52-68-6):
Hazard Codes: Xn Harmful ,N Dangerous
Risk Statements: 22-43-50/53
22: Harmful if swallowed
43: May cause sensitization by skin contact
50: Very Toxic to aquatic organisms
53: May cause long-term adverse effects in the aquatic environment
Safety Statements: 24-37-60-61-2
2: Keep out of the reach of children
24: Avoid contact with skin
37: Wear suitable gloves
60: This material and/or its container must be disposed of as hazardous waste
61: Avoid release to the environment. Refer to special instructions safety data sheet

Specification

Trichlorfon ,its CAS NO. is 52-68-6,the synonyms is (+-)-Trichlorfon ; (2,2,2-Trichloro-1-hydroxyethyl)-phosphonic acid dimethyl ester ; 1-Hydroxy-2,2,2-trichloro-ethyle phosphonate de dimethyle ; 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester ; AI3-19763 ; Agroforotox ; Anthon ; Bovinox ; Chlorophosciclosom ; Chlorophthalm ; Chloroxyphos ; Combot equine ; Dicontal Fort ; Dimethoxy-2,2,2-trichloro-1-hydroxy-ethyl phosphine oxide ; Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphonate ; Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate ; Dimethyl 1-hydroxy-2,2,2-trichloroethyl phosphonate ; Dimethyl 2,2,2-trichloro-1-hydroxyethylphosphonate ; Dimethyltrichlorohydroxyethyl phosphonate ; EPA Pesticide Chemical Code 057901 ; Equino-aid ; Fliegenteller ; Foschlorem ; Hypodermacid ; Khloroftalm ; Leivasom ; Loisol ; Methyl chlorophos ; Metriphonate ; Metriphonatum ; Neguvon ; O,O Dimetil 2,2,2-trichloro 1 hidroxietil fosfonato (Portugese) ; O,O-Dimethyl (1-hydroxy-2,2,2-trichloroethyl)phosphonate ; O,O-Dimethyl (1-oxy-2,2,2-trichloroethyl)phosphonate ; O,O-Dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate ; O,O-Dimethyl-(1-hydroxy-2,2,2-trichloraethyl)phosphonsaeure ester ; O,O-Dimethyl-(1-hydroxy-2,2,2-trichlorathyl)-phosphat ; O,O-Dimethyl-(2,2,2-trichloor-1-hydroxy-ethyl)-fosfonaat ; O,O-Dimethyl-(2,2,2-trichlor-1-hydroxy-aethyl)phosphonat ; O,O-Dimethyl-1-hydroxy-2,2,2-trichloroethylphosphonate ; O,O-Dimetil-(2,2,2-tricloro-1-idrossi-etil)-fosfonato ; OMS 800 ; Phoschlor ; Phoschlor R50 ; Phosphonic acid, (1-hydroxy-2,2,2-trichloroethyl)-, dimethyl ester ; Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, dimethyl ester ; Polfoschlor .