Products Categories
CAS No.: | 56-53-1 |
---|---|
Name: | Diethylstilbestrol |
Article Data: | 46 |
Molecular Structure: | |
Formula: | C18H20O2 |
Molecular Weight: | 268.356 |
Synonyms: | 4,4'-Stilbenediol,a,a'-diethyl-, (E)- (8CI);4,4'-Stilbenediol, a,a'-diethyl-, trans- (4CI);Phenol, 4,4'-(1,2-diethyl-1,2-ethenediyl)bis-,(E)-;(E)-3,4-Bis(4-hydroxyphenyl)-3-hexene;(E)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol;(E)-Diethylstilbestrol;4,4'-Dihydroxy-a,b-diethylstilbene;4,4'-Dihydroxydiethylstilbene;Agostilben;Antigestil;Bertrol;Bio-des;Bufon;Comestrol;Cyren;Cyren A;DEB;DES;DES (synthetic estrogen);Dawe's destrol;Di-Estryl;Diethylstilbestrol;Distilbene;Domestrol;Estrobene;Estromenin;Estrosyn;Fonatol;Hi-Bestrol;Microest;Milestrol;NSC 3070;Oestromensyl;Palestrol;Serral;Sexocretin;Sibol;Stilbetin;Stilboefral;Stilboestrol;Synthoestrin;Synthofolin;Syntofolin;trans-4,4'-Dihydroxy-a,b-diethylstilbene;trans-Diethylstilbestrol;trans-a,a'-Diethyl-4,4'-stilbenediol;a,a'-Diethyl-4,4'-stilbenediol;a,a'-Diethylstilbenediol; |
EINECS: | 200-278-5 |
Density: | 1.107 g/cm3 |
Melting Point: | 170-172 °C(lit.) |
Boiling Point: | 407.1 °C at 760 mmHg |
Flash Point: | 186.9 °C |
Solubility: | practically insoluble in water |
Appearance: | White solid |
Hazard Symbols: | T, N |
Risk Codes: | 45-61-36/37/38-51/53-40 |
Safety: | 53-36/37/39-45-60-61 |
Transport Information: | UN 3077 9/PG 3 |
PSA: | 40.46000 |
LogP: | 4.82860 |
Conditions | Yield |
---|---|
Stage #1: Diethylstilbestrol dimethyl ether With boron tribromide In dichloromethane at -78 - 20℃; for 2h; Inert atmosphere; Stage #2: With water In dichloromethane at 0℃; for 0.5h; | 63% |
With boron tribromide-dimethyl sulfide complex In 1,2-dichloro-ethane at 83.5℃; for 576h; | 50.2% |
With potassium hydroxide; Dipropylene glycol at 215 - 235℃; |
4-hydroxypropiophenone
A
diethylstilbestrol
B
3,4-bis(4-hydroxyphenyl)-3,4-hexanediol
C
cis-3,4-Bis(p-hydroxyphenyl)-3-hexene
Conditions | Yield |
---|---|
With titanium tetrachloride; zinc In tetrahydrofuran for 20h; Heating; Yield given; | A n/a B 27% C n/a |
With titanium tetrachloride; zinc In tetrahydrofuran for 20h; Heating; Yields of byproduct given; | A n/a B 27% C n/a |
With titanium tetrachloride; zinc In tetrahydrofuran for 20h; Heating; Yield given. Title compound not separated from byproducts; | A n/a B 27% C n/a |
ethylmagnesium iodide
4.4'-diethoxy-α.α'-diethyl-trans-stilbene
diethylstilbestrol
Conditions | Yield |
---|---|
at 190 - 200℃; |
Conditions | Yield |
---|---|
at 180 - 190℃; | |
at 180 - 190℃; |
ethylmagnesium iodide
diethylstilbestrol
Conditions | Yield |
---|---|
at 190 - 200℃; |
Conditions | Yield |
---|---|
at 190 - 200℃; |
Conditions | Yield |
---|---|
at 170 - 175℃; | |
at 170 - 175℃; | |
at 170 - 175℃; | |
at 170 - 175℃; |
Conditions | Yield |
---|---|
at 220℃; | |
at 220℃; |
Diethylstilbestrol dimethyl ether
A
diethylstilbestrol
B
(E)-4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-phenol
Conditions | Yield |
---|---|
With potassium hydroxide; ethoxyethoxyethanol |