Products Categories
CAS No.: | 571-36-8 |
---|---|
Name: | 5-androstene-3,17-dione |
Article Data: | 37 |
Molecular Structure: | |
Formula: | C19H26O2 |
Molecular Weight: | 286.414 |
Synonyms: | 5-Androsten-3,17-dione;NSC 12873;D5-Androstene-3,17-dione; |
Density: | 1.11 g/cm3 |
Melting Point: | 158 °C |
Boiling Point: | 423.7 °C at 760 mmHg |
Flash Point: | 158.4 °C |
PSA: | 34.14000 |
LogP: | 4.08740 |
Conditions | Yield |
---|---|
Oppenauer oxidation; | 85% |
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide for 1h; Ambient temperature; | 78% |
With sodium hydrogencarbonate; Dess-Martin periodane In dichloromethane; water at 25℃; for 2h; | 78% |
Conditions | Yield |
---|---|
Stage #1: Androstenedione With potassium tert-butylate In tert-butyl alcohol at 35 - 40℃; for 1.5h; Inert atmosphere; Stage #2: With acetic acid In water; tert-butyl alcohol at 20 - 25℃; Temperature; Reagent/catalyst; | 83% |
With potassium hydroxide; sodium hydrogencarbonate; acetic acid In 1,2-dimethoxyethane for 15h; Ambient temperature; | 75% |
With potassium tert-butylate; tert-butyl alcohol |
Conditions | Yield |
---|---|
With Celite; pyridinium chlorochromate In dichloromethane for 3.5h; Ambient temperature; Yields of byproduct given; | A n/a B 53% |
With chromic acid In acetone at 0℃; for 0.0666667h; Title compound not separated from byproducts; |
(8R,9S,10R,13S,14S)-6-bromo-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[α]phenanthrene-3,17(2H,6H)-dione
5-androstenedione
Conditions | Yield |
---|---|
With zinc In ethanol; water at 20℃; for 72h; Inert atmosphere; | 52% |
dehydroepiandrosterone
A
androst-4,6-diene-3,17-dione
B
5-androstenedione
C
Androsta-1,4-diene-3,17-dione
Conditions | Yield |
---|---|
With 2,2'-bipyridylchromium peroxide In benzene for 3h; Product distribution; Heating; effect of various chromium(VI) based oxidants; | A 40% B 10% C 8% |
With 2,2'-bipyridylchromium peroxide In benzene for 3h; Heating; | A 40% B 10% C 8% |
5-androstenedione
Conditions | Yield |
---|---|
With bromine; acetic acid anschliessendes Behandeln mit CrO3 und Erwaermen des Reaktionsprodukts mit Zink-Pulver und Methanol; |
Conditions | Yield |
---|---|
With sodium acetate; acetic acid In methanol; water at 25℃; Rate constant; Mechanism; μ = 0.09; |
Conditions | Yield |
---|---|
With sodium hydroxide; 3-oxo-Δ5-steroid isomerase In methanol; water Rate constant; pH 5.0 to 5.1; | |
With acetic acid; sodium chloride In methanol at 6.5℃; pH=3.9 - 5.1; Kinetics; Further Variations:; Temperatures; | |
With phosphate buffer; D38E mutant of 3-oxo-Δ5 steroid isomerase In methanol at 15.3℃; pH=7.0; Kinetics; Further Variations:; Temperatures; |
Conditions | Yield |
---|---|
nachfolgendes Behandeln mit CrO3 und Erwaermen des Reaktionsprodukts mit Zink-Pulver und Methanol; |
What can I do for you?
Get Best Price
The CAS register number of Androst-5-ene-3,17-dione is 571-36-8. It also can be called as 5-Androsten-3,17-dione and the systematic name about this chemical is androst-5-ene-3,17-dione. The molecular formula about this chemical is C19H26O2 and the molecular weight is 286.4085. This chemical can be used in biochemistry.
Physical properties about Androst-5-ene-3,17-dione are: (1)ACD/LogP: 3.01; (2)ACD/LogD (pH 5.5): 3.01; (3)ACD/LogD (pH 7.4): 3.01; (4)ACD/BCF (pH 5.5): 113.59; (5)ACD/BCF (pH 7.4): 113.59; (6)ACD/KOC (pH 5.5): 1029.98; (7)ACD/KOC (pH 7.4): 1029.98; (8)#H bond acceptors: 2; (9)Polar Surface Area: 34.14Å2; (10)Index of Refraction: 1.551; (11)Molar Refractivity: 81.71 cm3; (12)Molar Volume: 255.8 cm3; (13)Polarizability: 32.39x10-24cm3; (14)Surface Tension: 42.6 dyne/cm; (15)Enthalpy of Vaporization: 67.81 kJ/mol; (16)Boiling Point: 423.7 °C at 760 mmHg; (17)Vapour Pressure: 2.19E-07 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES: O=C4C/C3=C/C[C@@H]2[C@H](CC[C@@]1(C(=O)CC[C@H]12)C)[C@@]3(C)CC4
(2)InChI: InChI=1/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,14-16H,4-11H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
(3)InChIKey: SQGZFRITSMYKRH-QAGGRKNEBS
(4)Std. InChI: InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,14-16H,4-11H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
(5)Std. InChIKey: SQGZFRITSMYKRH-QAGGRKNESA-N