Products Categories
CAS No.: | 607-35-2 |
---|---|
Name: | 8-Nitroquinoline |
Article Data: | 37 |
Molecular Structure: | |
Formula: | C9H6N2O2 |
Molecular Weight: | 174.159 |
Synonyms: | 8-Nitroqunioline;quinoline, 8-nitro-;5-20-07-00327 (Beilstein Handbook Reference); |
EINECS: | 210-135-9 |
Density: | 1.354 g/cm3 |
Melting Point: | 89-91 °C(lit.) |
Boiling Point: | 323.1 °C at 760 mmHg |
Flash Point: | 149.2 °C |
Solubility: | Soluble in ethanol, ethyl ether and benzene, slightly soluble in cold water. |
Appearance: | white to light yellow crystal powder |
Hazard Symbols: | Xn, Xi |
Risk Codes: | 20/21/22-36/37/38-40-68 |
Safety: | 26-27-36/37/39-36 |
PSA: | 58.71000 |
LogP: | 2.66620 |
Conditions | Yield |
---|---|
With N-Bromosuccinimide; [bis(trifluoroacetoxy)iodo]benzene; sodium nitrite In acetonitrile at 20℃; for 3h; regioselective reaction; | 84% |
Conditions | Yield |
---|---|
Stage #1: 2-nitro-aniline; glycerol With sodium iodide at 20℃; for 0.0833333h; Stage #2: With sulfuric acid for 0.166667h; Cooling with ice; Stage #3: at 140℃; for 2h; | 81% |
Stage #1: 2-nitro-aniline With sulfuric acid at 70 - 80℃; Stage #2: glycerol at 70 - 80℃; Temperature; Further stages; | 79% |
With sulfuric acid In water for 4h; Reflux; | 72% |
8-nitro-1,2,3,4-tetrahydroquinoline
8-nitroquinoline
Conditions | Yield |
---|---|
With iodine; oxygen In 1,2-dichloro-benzene; toluene at 160℃; for 30h; | 77% |
Conditions | Yield |
---|---|
With sulfuric acid In water; glycerol Reflux; | 44% |
Conditions | Yield |
---|---|
Stage #1: quinoline With sulfuric acid; nitric acid at 20℃; for 1h; Stage #2: With sodium carbonate In water | A 34% B 38% |
With sulfuric acid; nitric acid In water at 0 - 20℃; for 1h; | A 35% B n/a |
With sulfuric acid; nitric acid |
Conditions | Yield |
---|---|
durch Nitrieren; |
8-nitroquinoline
Conditions | Yield |
---|---|
With ammonia at 130 - 140℃; im Rohr; |
Conditions | Yield |
---|---|
With phosphoric acid; water; orthoarsenic acid | |
With hydrogenchloride; phosphoric acid In water at 80 - 95℃; for 7h; |
Conditions | Yield |
---|---|
With nitric acid at 160℃; im Rohr; |
1. | mmo-sat 50 µg/plate | MUREAV Mutation Research. 39 (1977),285. | ||
2. | mma-sat 100 nmol/plate | MUREAV Mutation Research. 58 (1978),11. | ||
3. | dnr-sat 350 µg/disc | MUREAV Mutation Research. 39 (1977),285. | ||
4. | orl-rat TD:36,400 mg/kg/2Y-C:CAR,REP | CALEDQ Cancer Letters (Shannon, Ireland). 14 (1981),115. | ||
5. | ipr-mus LDLo:125 mg/kg | CBCCT* “Summary Tables of Biological Tests“ National Research Council Chemical-Biological Coordination Center. 6 (1954),149. |