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CAS No.: | 620-71-3 |
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Name: | PROPIONANILIDE |
Article Data: | 237 |
Molecular Structure: | |
Formula: | C9H11 N O |
Molecular Weight: | 149.192 |
Synonyms: | Propionanilide(6CI,7CI,8CI); N-Phenylpropanamide; N-Phenylpropionamide; NSC 58952; R 50977 |
Density: | 1.073g/cm3 |
Melting Point: | 104-107℃ |
Boiling Point: | 314.4°C at 760 mmHg |
Flash Point: | 182°C |
Solubility: | Insoluble in water. |
Safety: | Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. |
PSA: | 29.10000 |
LogP: | 2.10810 |
propiophenone oxime
N-(phenyl)-2-methylacetamide
Conditions | Yield |
---|---|
With sulfuric acid; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate for 0.0166667h; Beckmann rearrangement; microwave irradiation; | 100% |
mercury dichloride In acetonitrile at 80℃; for 8h; Beckmann rearrangement; | 98% |
With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; zinc(II) chloride In acetonitrile for 1h; Beckmann rearrangement; Heating; | 97% |
Conditions | Yield |
---|---|
With 1,1'-carbonyldiimidazole; methyl iodide In acetonitrile for 1h; Heating; | 98% |
With p-toluenesulfonyl chloride; zinc(II) chloride In acetonitrile for 1h; Beckmann rearrangement; Inert atmosphere; Reflux; | 98% |
With silica gel; caesium carbonate; N-tosylimidazole In N,N-dimethyl-formamide for 2h; Beckmann rearrangement; Reflux; | 98% |
Conditions | Yield |
---|---|
With fluorosulfonyl fluoride; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 5h; | 98% |
Stage #1: propionic acid With iodine; triethylamine; phosphorous acid trimethyl ester In dichloromethane for 0.166667h; Cooling with ice; Inert atmosphere; Stage #2: aniline In dichloromethane at 20℃; for 3h; Inert atmosphere; Cooling with ice; | 96% |
With [((CH3)5Cp)2Zr(H2O)2OSO2C8F17]+[OSO2C8F17]-*THF In neat (no solvent) at 80℃; for 2h; | 94% |
Conditions | Yield |
---|---|
With palladium(II) acetylacetonate In toluene at 100℃; under 30003 Torr; for 20h; Autoclave; Inert atmosphere; regioselective reaction; | 98% |
With C52H52NO5P; palladium(II) iodide In tetrahydrofuran at 60℃; under 760.051 Torr; for 72h; Autoclave; regioselective reaction; | 93% |
With Ru-clusters supported on ceria In tetrahydrofuran at 160℃; under 7500.75 Torr; for 24h; Autoclave; | 67% |
Co/C In water at 150℃; under 53203.6 Torr; for 72h; | 54% |
benzenediazonium tetrafluoroborate
propiononitrile
N-(phenyl)-2-methylacetamide
Conditions | Yield |
---|---|
Stage #1: benzenediazonium tetrafluoroborate; propiononitrile for 0.0166667h; Microwave irradiation; Stage #2: With water In diethyl ether | 97% |
Conditions | Yield |
---|---|
With oxygen; sodium hydroxide In water at 40℃; for 24h; | 97% |
With oxygen; sodium hydroxide In water at 40℃; for 24h; Green chemistry; | 94% |
With potassium tert-butylate In 1,4-dioxane at 110℃; for 24h; | 88% |
Conditions | Yield |
---|---|
With tris(pentafluorophenyl)borate In neat (no solvent) at 20℃; for 0.0333333h; Green chemistry; | 96% |
With sodium dodecyl-sulfate In water | 87% |
Conditions | Yield |
---|---|
With trifluorormethanesulfonic acid; hydroxylamine hydrochloride In formic acid for 7h; Heating; | 96% |
With sodium azide; sulfuric acid; silica gel at 60℃; for 0.5h; Schmidt reaction; | 95% |
With zinc(II) chloride; hydroxylamine-O-sulfonic acid In water at 20℃; for 16h; Beckmann Rearrangement; | 93% |
Conditions | Yield |
---|---|
With triphenylphosphine In benzene for 60h; Heating; | 96% |
With triethylphosphine In benzene at 80℃; for 12h; | 87% |
Conditions | Yield |
---|---|
With hydrogen for 1h; | 94% |
Propionanilide is also named as n-phenyl-propanamid;N-Phenylpropanamide;Propionamide, N-phenyl-;Propionic anilide,and so on.
Molecular Formula: C9H11NO
Molecular Weight: 149.19
EINECS: 210-649-3
Test type: LD50 - Lethal dose, 50 percent kill
Contact: Oral
Species: Rodent - mouse
Dose: 1100 mg/kg
Toxic effect:Details of toxic effects not reported other than lethal dose value
Referrence: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,20,1971
RTECS:UE4600000
Reported in EPA TSCA Inventory.
EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998