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66774-02-5

Basic Information
CAS No.: 66774-02-5
Name: CLOTRIMAZOLE IMP. A (PHARMEUROPA): (2-CHLOROPHENYL)DIPHENYLMETHANOL
Article Data: 20
Molecular Structure:
Molecular Structure of 66774-02-5 (CLOTRIMAZOLE IMP. A (PHARMEUROPA): (2-CHLOROPHENYL)DIPHENYLMETHANOL)
Formula: C19H15 Cl O
Molecular Weight: 294.78
Synonyms: Methanol,(o-chlorophenyl)diphenyl- (6CI); (2-Chlorophenyl)diphenylmethanol; NSC 170882;TRAM 3; o-Chlorophenyldiphenylmethanol
Density: 1.216g/cm3
Melting Point: 91-92 °C(Solv: acetic acid (64-19-7))
Boiling Point: 447.6°C at 760 mmHg
Flash Point: 224.5°C
PSA: 20.23000
LogP: 4.62420
Synthetic route
23593-75-1

clotrimazole

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
With hydrogenchloride for 2h; Heating;93%
With hydrogenchloride; water for 3h; Heating / reflux;85%
With hydrogenchloride In water; isopropyl alcohol for 17h; Heating;36%
23593-75-1

clotrimazole

A

288-32-4

1H-imidazole

B

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
With hydrogenchloride In water; acetonitrile at 80℃; for 2h;A n/a
B 71%
5162-03-8

(2-chlorophenyl)(phenyl)methanone

100-58-3

phenylmagnesium bromide

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
Stage #1: phenylmagnesium bromide With zinc(II) chloride In tetrahydrofuran at 20℃; for 1h;
Stage #2: (2-chlorophenyl)(phenyl)methanone In tetrahydrofuran for 120h; Reflux;
58%
119-61-9

benzophenone

615-41-8

2-iodochlorobenzene

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
With (trimethylsilyl)methylmagnesium chloride In tetrahydrofuran at 20℃; for 12h;32%
36692-27-0

2-chlorophenylmagnesium bromide

119-61-9

benzophenone

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
With diethyl ether
119-61-9

benzophenone

33432-65-4

2-chlorophenyllithium

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
With diethyl ether
610-96-8

methyl chlorobenzoate

phenylmagnesium bromide

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
With diethyl ether
60-29-7

diethyl ether

7335-25-3

ethyl 2-chlorobenzoate

phenylmagnesium bromide

A

95950-06-4

1,2-bis-(2-chloro-phenyl)-1,2-diphenyl-ethane-1,2-diol

B

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
at 50℃;
3509-85-1

1-chloro-2-(dichloro(phenyl)methyl)benzene

71-43-2

benzene

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
With aluminium trichloride at 20℃; for 22h;
5162-03-8

(2-chlorophenyl)(phenyl)methanone

66774-02-5

o-chlorotriphenylmethanol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: PCl5 / 2 h / 130 - 140 °C
2: AlCl3 / 22 h / 20 °C
View Scheme
With phenyllithium In cyclohexane-Et2 O; diethyl ether23.1 g (78%)
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    (o-Chlorophenyl)diphenylmethanol Application:836384

    PureChems is dedicated to bring high quality and cost effective chemical products and services to our clients. PureChems can provide high purity Natural Products, Research Chemical

  • Pure Chemistry Scientific Inc.

    United States  |  Contact Details

    Business Type:Trading Company

    Tel:+1-857-366-7588

    Address:14905 SW freeway street #232, Sugarland, TX 77478, USA

       Inquiry Now

  • Clotrimazole impurity A

  • Casno:

    66774-02-5

    Clotrimazole impurity A

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Impurities from EP, CP, USP, JP, IP and independent R&D Package:10mg, 25mg, 50mg, 100mg, Other scale please send an equiry Application:For research and development purpose Port:Guangzhou

    Guangzhou Pi & Pi Biotech Inc. was set up in Guangzhou Privately-Run Science and Technology Park In 2009. Currently, the company and its R & D Centre are located in the South Ch

  • Guangzhou PI & PI Biotech Inc. Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-20-81716320

    Address:Suite 501,198 Kaiyuan Ave.,Science City, Guangzhou,China

       Inquiry Now

  • Clotrimazole EP Impurity A

  • Casno:

    66774-02-5

    Clotrimazole EP Impurity A

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    1. Our staff are all biomedical related majors with rich experience in the pharmaceutical industry, and can provide you with more professional services.2. Our supplier has a good quality management system, and the quality of products is reliable and

  • Shenzhen Sumshine Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:15914108025

    Address:229A, No.15, Xinbeli Industrial Zone, Xinshi Community, Dalang Street, Longhua District

       Inquiry Now

  • Clotrimazole Impurity A

  • Casno:

    66774-02-5

    Clotrimazole Impurity A

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    High purity Application:Pharmaceutical intermediates, Material synthesis and analyzing the expectant ingredients

    Novachemistry offers a broad range of specialty chemicals and customized synthesis services to a range of pharmaceutical, agrochemical and biochemical industries. Novachemistry has

  • NovaChemistry

    United Kingdom  |  Contact Details

    Business Type:Trading Company

    Tel:+44 (0)208 191 7890

    Address:Unit11, Ark Business Centre, Gorden Road, Loughborough, United Kingdom

       Inquiry Now

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