Products Categories
| CAS No.: | 72811-73-5 |
|---|---|
| Name: | 4-(3'-Methylphenyl)amino-3-pyridinesulfonamide |
| Article Data: | 5 |
| Molecular Structure: | |
|
|
|
| Formula: | C12H13N3O2S |
| Molecular Weight: | 263.32 |
| Synonyms: | 3-Sulfonamido-4-(3-methylanilino)pyridine;BM 960102;4-(3-methylphenyl)amino-3-pyridine sulfonamide; |
| EINECS: | 615-805-8 |
| Density: | 1.357 g/cm3 |
| Melting Point: | 162-164oC |
| Boiling Point: | 475.8 °C at 760 mmHg |
| Flash Point: | 241.5 °C |
| Hazard Symbols: | Xi |
| Risk Codes: | 36 |
| Safety: | 26 |
| PSA: | 93.46000 |
| LogP: | 3.63510 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 33263-43-3
4-chloropyridine-3-sulphonamide
- 108-44-1
1-amino-3-methylbenzene
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
| Conditions | Yield |
|---|---|
| In methanol at 39.85℃; for 3h; | 96.5% |
| In propan-1-ol for 5h; Heating; | |
| In water at 80 - 90℃; for 1 - 1.5h; Product distribution / selectivity; | |
| Stage #1: 4-chloropyridine-3-sulphonamide; 1-amino-3-methylbenzene In water for 0.5h; Heating / reflux; Stage #2: With sodium hydroxide In water at 20 - 35℃; Stage #3: With sulfuric acid In water Product distribution / selectivity; |
- 777854-85-0
4-chloro-3-pyridinesulfonamide hydrochloride
- 108-44-1
1-amino-3-methylbenzene
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
| Conditions | Yield |
|---|---|
| Stage #1: 4-chloro-3-pyridinesulfonamide hydrochloride; 1-amino-3-methylbenzene In water at 90℃; for 3h; Stage #2: With sodium hydrogencarbonate In water at 20℃; pH=7 - 8; | 92% |
- 625-95-6
3-Iodotoluene
- 75903-62-7
3-sulfonamido-4-aminopyridine
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
| Conditions | Yield |
|---|---|
| With copper; potassium carbonate In butan-1-ol | 53.1% |
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
- 1795-48-8
Isopropyl isocyanate
| Conditions | Yield |
|---|---|
| Stage #1: 3-sulfonamido-4-(3'-methylphenyl) aminopyridine With sodium hydride In tetrahydrofuran; toluene at 5 - 20℃; for 16h; Stage #2: Isopropyl isocyanate In tetrahydrofuran; toluene at 20℃; Stage #3: Isopropyl isocyanate With sodium hydride; acetic acid more than 3 stages; | 100% |
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
- 1795-48-8
Isopropyl isocyanate
- 56211-40-6
torasemide
| Conditions | Yield |
|---|---|
| Stage #1: 3-sulfonamido-4-(3'-methylphenyl) aminopyridine; Isopropyl isocyanate With potassium carbonate In diethylene glycol dimethyl ether; water at 65 - 70℃; for 0.583333h; Stage #2: With acetic acid In diethylene glycol dimethyl ether; water at 20 - 25℃; for 3h; pH=5.3 - 5.7; | 96.5% |
| Stage #1: 3-sulfonamido-4-(3'-methylphenyl) aminopyridine; Isopropyl isocyanate With sodium hydroxide In acetone at 20 - 30℃; Stage #2: With acetic acid In water; acetone at 20 - 25℃; for 0.25h; pH=5.3 - 5.7; | 96% |
| Stage #1: 3-sulfonamido-4-(3'-methylphenyl) aminopyridine; Isopropyl isocyanate With sodium hydroxide In acetone at 20 - 30℃; Stage #2: With acetic acid In water; acetone at 20 - 25℃; for 0.25h; pH=5.5; | 96% |
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
- 1795-48-8
Isopropyl isocyanate
| Conditions | Yield |
|---|---|
| With sodium hydroxide In acetone at 5 - 20℃; for 2h; Reagent/catalyst; | 94.5% |
- 17614-10-7
phenyl N-isopropylcarbamate
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
- 56211-40-6
torasemide
| Conditions | Yield |
|---|---|
| Stage #1: phenyl N-isopropylcarbamate; 3-sulfonamido-4-(3'-methylphenyl) aminopyridine With triethylamine In water; acetone for 3h; Heating / reflux; Stage #2: With sodium hydroxide In water at 20 - 25℃; Stage #3: With sulfuric acid In water; acetone at 50 - 55℃; for 1h; Product distribution / selectivity; | 87.8% |
| Stage #1: phenyl N-isopropylcarbamate; 3-sulfonamido-4-(3'-methylphenyl) aminopyridine With sodium hydroxide In water at 90 - 100℃; for 5h; Stage #2: With sulfuric acid In water at 20 - 70℃; for 1h; Product distribution / selectivity; | 85% |
| Stage #1: 3-sulfonamido-4-(3'-methylphenyl) aminopyridine With sodium hydroxide In water at 20 - 35℃; Stage #2: phenyl N-isopropylcarbamate In water; acetone at 50 - 60℃; for 20h; Stage #3: With sulfuric acid In water at 15 - 50℃; for 3h; pH=7.0; Product distribution / selectivity; |
- 541-41-3
chloroformic acid ethyl ester
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
- 72810-57-2
[4-(3-methyl-anilino)-pyridine-3-sulfonyl]-carbamic acid ethyl ester
| Conditions | Yield |
|---|---|
| With pyridine for 0.333333h; Heating; | 75% |
| In tetrahydrofuran for 8h; Ambient temperature; |
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
- 5848-27-1
N-cyano-N'-isopropyl-S-methylcarbamimidothioate
| Conditions | Yield |
|---|---|
| With sodium hydroxide In 1,4-dioxane; N,N-dimethyl-formamide for 6h; Heating; | 37% |
- 72811-73-5
3-sulfonamido-4-(3'-methylphenyl) aminopyridine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 75 percent / pyridine / 0.33 h / Heating 2: 37 percent / toluene / 5 h / Heating View Scheme |
What can I do for you?
Get Best Price
Chemistry
Empirical Formula: C12H13N3O2S
Molecular Weight: 263.3155g/mol
Structure of 3-Pyridinesulfonamide,4-[(3-methylphenyl)amino]- (CAS NO.72811-73-5):
Index of Refraction: 1.641
Molar Refractivity: 69.97 cm3
Molar Volume: 193.9 cm3
Polarizability: 27.73×10-24cm3
Surface Tension: 63.3 dyne/cm
Density: 1.357 g/cm3
Flash Point: 241.5 °C
Enthalpy of Vaporization: 73.94 kJ/mol
Boiling Point: 475.8 °C at 760 mmHg
Vapour Pressure: 3.23E-09 mmHg at 25°C
Product Categories: INTERMEDIATESOFTORASEMIDE;Pyridines derivates;(intermediate of torasemide);Pyridines;Torsemide
Systematic Name: 4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
SMILES: O=S(=O)(c2c(Nc1cc(ccc1)C)ccnc2)N
InChI: InChI=1/C12H13N3O2S/c1-9-3-2-4-10(7-9)15-11-5-6-14-8-12(11)18(13,16)17/h2-8H,1H3,(H,14,15)(H2,13,16,17)
InChIKey: ZXPCUGWAKUIOOF-UHFFFAOYAX
Specification
3-Pyridinesulfonamide,4-[(3-methylphenyl)amino]- , its cas register number is 72811-73-5. It also can be called ; 4-[(3-Methylphenyl)amino]pyridine-3-sulfonamide ; 3-Sulfonamido-4-(3-methylanilino)pyridine ; 4-(3-Methylphenyl)amino-3-Pyridine Sulfonamide ; 4-(3-toluidino)pyridine-3-sulfonamide .