CAS No.774-74-3,2-(2,6-DICHLOROPHENOXY)ACETYL CHLORIDE Suppliers

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Basic Information

Molecular Structure:
CAS No.:	774-74-3
Name:	2-(2,6-DICHLOROPHENOXY)ACETYL CHLORIDE
Article Data:	68

Formula:	C₈H₅Cl₃O₂
Molecular Weight:	239.485
Synonyms:	Acetylchloride, (2,4-dichlorophenoxy)- (6CI,7CI,8CI,9CI);(2,4-Dichlorophenoxy)acetylchloride;2-(2,4-Dichlorophenyloxy)acetyl chloride;
EINECS:	212-268-8
Density:	1.475 g/cm³
Boiling Point:	296.4 °C at 760 mmHg
Flash Point:	126.3 °C
PSA:	26.30000
LogP:	3.13760

Synthetic route

: 94-75-7
2,4-Dichlorophenoxyacetic acid

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

Conditions

Conditions	Yield
With thionyl chloride at 100℃; for 5h; Substitution;	100%
With thionyl chloride; N-benzyl-N,N,N-triethylammonium chloride In chloroform for 4h; Chlorination; Heating;	85%
With thionyl chloride at 75℃; for 2h;	80%

: 120-83-2
2,4-dichlorophenol

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 77 percent / NaOH / H2O / 3 h / 110 - 120 °C 2: SOCl2 View Scheme
Multi-step reaction with 2 steps 1: 33percent aq. NaOH / 1 h / Heating 2: SOCl2 / CHCl3 / 6 h / Heating View Scheme
Multi-step reaction with 2 steps 1: aq. NaOH / 0.5 h / Heating 2: SOCl2 / benzene; ethyl acetate / 6 h / Heating View Scheme

: 120-83-2
2,4-dichlorophenol

sodium-salt of/the/ 3-formyl-benzenesulfonic acid: sodium-salt of/the/ 3-formyl-benzenesulfonic acid

A: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

B silver-salt of/the/ <2,4-dichloro-phenoxy>-acetic acid: silver-salt of/the/ <2,4-dichloro-phenoxy>-acetic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: K2CO3; KI; PEG-600 / toluene / 1.5 h / 100 °C 1.2: 94 percent / HCl / H2O / 60 °C 2.1: 85 percent / SOCl2; benzyltriethylammonium chloride / CHCl3 / 4 h / Heating View Scheme

...Expand

: 3757-76-4
sodium 2,4-dichlorophenolate

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: ethyl acetate 2: thionyl chloride / 8 h / Heating View Scheme

: 120-83-2
2,4-dichlorophenol

(+-)-3,4-dihydro-2H-pyran-2-carboxylic acid ethyl ester: (+-)-3,4-dihydro-2H-pyran-2-carboxylic acid ethyl ester

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: NaOH / H2O / Heating 2: SOCl2 / ethyl acetate; methanol / 7 h / Heating View Scheme

: 5-[2-chloro-4-(trifluoromethyl)phenoxy]benzoyl chloride

A: 77207-06-8
2-hydroxyethyl 5-(2-chloro-4-trifluoromethyl phenoxy)-2-nitrobenzoate

B: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

Conditions

Conditions	Yield
With triethylamine In dichloromethane; ethylene glycol

: 533-23-3
ethyl 2,4-dichlorophenoxyacetate

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium hydroxide 2: thionyl chloride / Reflux View Scheme

: 1928-38-7
methyl 2,4-dichlorophenoxyacetate

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: lithium hydroxide / methanol; water / 12 h / 50 °C 2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 12 h / 20 °C View Scheme

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

: 92-87-5
p,p'-diaminobiphenyl

: 2-(2,4-dichloro-phenoxy)-N-{4'-[2-(2,4-dichloro-phenoxy)-acetylamino]-biphenyl-4-yl}-acetamide

Conditions

Conditions	Yield
With sodium hydroxide; PEG-600 In dichloromethane; water at 20℃; for 1h; Acylation;	99%

: 119-93-7
o-tolidin

: 774-74-3
2-(2,4-dichlorophenoxy)acetyl chloride

: 2-(2,4-dichloro-phenoxy)-N-{4'-[2-(2,4-dichloro-phenoxy)-acetylamino]-3,3'-dimethyl-biphenyl-4-yl}-acetamide

Conditions

Conditions	Yield
With sodium hydroxide; PEG-600 In dichloromethane; water at 20℃; for 1h; Acylation;	98%

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Specification

The Acetyl chloride,2-(2,4-dichlorophenoxy)- is an organic compound with the formula C₈H₅Cl₃O₂. The IUPAC name of this chemical is 2-(2,4-dichlorophenoxy)acetyl chloride. With the CAS registry number 774-74-3, it is also named as 2,4-Dichlorophenoxyacetyl chloride.

Physical properties about Acetyl chloride,2-(2,4-dichlorophenoxy)- are: (1)ACD/LogP: 3.32; (2)ACD/LogD (pH 5.5): 3.32; (3)ACD/LogD (pH 7.4): 3.32; (4)ACD/BCF (pH 5.5): 195.7; (5)ACD/BCF (pH 7.4): 195.7; (6)ACD/KOC (pH 5.5): 1520.29; (7)ACD/KOC (pH 7.4): 1520.29; (8)#H bond acceptors: 2; (9)#Freely Rotating Bonds: 3; (10)Polar Surface Area: 26.3 Å²; (11)Index of Refraction: 1.556; (12)Molar Refractivity: 52.23 cm³; (13)Molar Volume: 162.3 cm³; (14)Polarizability: 20.7×10^-24cm³; (15)Surface Tension: 44.3 dyne/cm; (16)Density: 1.475 g/cm³; (17)Flash Point: 126.3 °C; (18)Enthalpy of Vaporization: 53.62 kJ/mol; (19)Boiling Point: 296.4 °C at 760 mmHg; (20)Vapour Pressure: 0.00144 mmHg at 25°C.

Preparation: this chemical can be prepared by (2,4-dichloro-phenoxy)-acetic acid. This reaction will need reagent SOCl₂.

Uses of Acetyl chloride,2-(2,4-dichlorophenoxy)-: it can be used to produce N-(2-vinyloxyethyl)-2,4-dichlorophenoxyacetamide at temperature of 40 - 45 °C. It will need reagent Et₃N and solvent benzene with reaction time of 30 min. The yield is about 62%.

You can still convert the following datas into molecular structure:
(1)SMILES: Clc1cc(Cl)ccc1OCC(Cl)=O
(2)InChI: InChI=1/C8H5Cl3O2/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2
(3)InChIKey: FUJSJWRORKKPAI-UHFFFAOYAT
(4)Std. InChI: InChI=1S/C8H5Cl3O2/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2
(5)Std. InChIKey: FUJSJWRORKKPAI-UHFFFAOYSA-N