1670-17-3Relevant articles and documents
N,N-Dimethyl-2,4-dinitroaniline
Low,Doidge-Harrison,Cobo
, p. 964 - 966 (1996)
The title compound, C8H9N3O4, has both the o-nitro group and the 1-dimethylamino group twisted out of the plane of the benzene ring, whereas the p-nitro group is almost coplanar with the ring.
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Weber
, p. 763 (1877)
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General method for nucleophilic aromatic substitution of aryl fluorides and chlorides with dimethylamine using hydroxide-assisted decomposition of N,N-dimethylforamide
Garcia, Juana,Sorrentino, Jacob,Diller, Emily J.,Chapman, Daniel,Woydziak, Zachary R.
supporting information, p. 475 - 481 (2016/04/05)
A practical and convenient procedure for the nucleophilic aromatic substitution of aryl fluorides and chlorides with dimethylamine was developed using a hydroxide-assisted thermal decomposition of N,N-dimethylforamide. These conditions are tolerant of nitro, nitrile, aldehyde, ketone, and amide groups but will undergo acyl substitution to form amides for methyl esters and acyl chlorides. Isolated yields of the products range from 44% to 98%, with the majority being greater than 70% for 17 examples.
First Application of Heterogeneous Cobalt Catalysis in Csp2-N Cross-Coupling of Activated Chloroarenes under Ligand-Free Conditions
Mukherjee, Nirmalya,Chatterjee, Tanmay,Ranu, Brindaban C.
, p. 4018 - 4023 (2015/06/30)
A heterogeneous CoII/Al2O3 catalyst efficiently catalyses the N-arylation of N-heterocycles and open-chain secondary amines by activated chloroarenes and chloroheteroarenes under ligand-free conditions in water to give a series of functionalized tertiary amines. The catalyst was prepared by immobilizing CoBr2 onto the surface of Al2O3, and was characterized by X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy, and energy-dispersive X-ray analysis. This catalyst could be recycled up to six times without any appreciable loss of catalytic activity. A heterogeneous CoII/Al2O3 catalyst efficiently catalyses the N-arylation of N-heterocycles and open- or closed-chain secondary amines by activated chloroarenes and chloroheteroarenes under ligand-free conditions in water to give a series of functionalized tertiary amines.
