17180-94-8Relevant articles and documents
Bridged Hydroquinolines
Balasubrahmanyam, S. N.,Jeyashri, B.
, p. 559 - 562 (2007/10/02)
The pyridannulation procedure of condensing vinamidinium salts with ketones having a free α-methylene has been adapted to prepare 3-substituted 5,6,7,8-tetrahydroquinolines; characterization data for the seven systems synthesized are reported.Conditions required are less drastic than those for recently reported alternative approaches to analogous systems.The adaption has considerable generality even though 5,8-methano-bridged 5,6,7,8-tetrahydroquinolines are not accessible through it.Chirality in the starting ketone, not affected by exposure to enolizing conditions, is preserved in the pyridannulated products.
Process for preparing 5-halopyrimidines
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, (2008/06/13)
The reaction of formamide at high temperature with a 4-halo-5-hydroxy-2(5H)-furanone provides high yields of 5-chloro or 5-bromopyrimidines.
Reactions of Halogenomethanes in the Vapour Phase. Part 5. The Reactions of Imidazolines, Anils, and 1-Methylimidazole with Chloroform at 550 deg C, and a Comparison with their Liquid-Phase Reactions with Trichloroacetate Ion or Hexachloroacetone and Base
Busby, Reginald E.,Khan, Mohammad A.,Khan, Mohammad R.,Parrick, John,Shaw, C. J. Granville
, p. 1431 - 1435 (2007/10/02)
The vapor-phase reactions of imidazolines and anils with chloroform at 550 deg C are compared with their liquid-phase reactions in the presence of hexachloroacetone and base or upon thermolysis with trichloroacetate ion.In the vapour-phase reactions imidazolines, unlike imidazoles, gave non-chlorinated pyrimidines, and 1-methyl-imidazole gave 2-cyanopyrrole and the four 3-chlorocyanopyridines.
