1000210-73-0

Basic information

• Product Name: (3,5-dichloro-benzylidene)-(2,2-diethoxy-ethyl)-amine
• Synonyms: (3,5-dichloro-benzylidene)-(2,2-diethoxy-ethyl)-amine
• CAS NO: 1000210-73-0
• Molecular Weight: 290.189
• Mol File: 1000210-73-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (3,5-dichloro-benzylidene)-(2,2-diethoxy-ethyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-dichloro-benzylidene)-(2,2-diethoxy-ethyl)-amine(1000210-73-0)
• EPA Substance Registry System: (3,5-dichloro-benzylidene)-(2,2-diethoxy-ethyl)-amine(1000210-73-0)

Safety Data

• Hazardous Substances Data: 1000210-73-0(Hazardous Substances Data)

Upstream product

• 10203-08-4 3,5-dichlorobenzaldehyde 
• 645-36-3 2,2-diethoxy-ethanamine 

Downstream Products

• 1289646-93-0 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid hydrochloride 
• 1025967-78-5 (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 
• 1194550-67-8 ((S)-benzyl 2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-methylsulfonyl)phenyl)propanoate 
• 1194550-56-5 5,7-dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid 
• 1289646-72-5 C₂₈H₂₃Cl₂N 
• 1194550-65-6 benzyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-[3-(methylsulfonyl)phenyl]propanoate hydrochloride 
• 1194550-63-4 C₄₆H₄₀Cl₂N₂O₅S 
• 73075-47-5 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline hydrochloride 
• 851784-82-2 2-(tert-butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid 
• 73075-58-8 5,7-dichloro isoquinoline 

Relevant articles and documents

Preparation method of 5, 7-dichloro-1, 2, 3, 4-tetrahydroisoquinoline

The invention provides a preparation method of 5, 7-dichloro-1, 2, 3, 4-tetrahydroisoquinoline. The preparation method comprises the following steps: preparing a compound A by taking 3, 5-dichlorobenzoic acid as a raw material; preparing a compound B from the compound A; preparing a compound C from the compound B; preparing a compound D from the compound C; and obtaining a white solid 5, 7-dichloro-1, 2, 3, 4-tetrahydroisoquinoline from the compound D. The preparation method of 5, 7-dichloro-1, 2, 3, 4-tetrahydroisoquinoline provided by the invention has the advantages of high product purity and high product yield.

LFA-1 INHIBITOR AND POLYMORPH THEREOF

Methods of preparation and purification of a compound, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA -1 mediated diseases are also disclosed.