73075-47-5 Usage
General Description
5,7-Di-Chloro-1,2,3,4-tetrahydroisoquinoline HCL is a chemical compound that consists of a tetrahydroisoquinoline ring with two chlorine atoms attached at the 5 and 7 positions. It is commonly used as a reagent in organic synthesis and pharmaceutical research. 5,7-Di-Chloro-1,2,3,4-tetrahydroisoquinoline HCL is known for its potential pharmacological activities, particularly in the field of central nervous system disorders and pain management. It is also used as a precursor in the synthesis of various pharmaceutical drugs and is often employed in the development of new therapeutic agents. Additionally, 5,7-Di-Chloro-1,2,3,4-tetrahydroisoquinoline HCL is considered a valuable building block for the synthesis of diverse heterocyclic compounds with potential biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 73075-47-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,0,7 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 73075-47:
(7*7)+(6*3)+(5*0)+(4*7)+(3*5)+(2*4)+(1*7)=125
125 % 10 = 5
So 73075-47-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H9Cl2N.ClH/c10-7-3-6-5-12-2-1-8(6)9(11)4-7;/h3-4,12H,1-2,5H2;1H
73075-47-5Relevant articles and documents
Scalable Process for Making 5,7-Dichlorotetrahydroisoquinoline-6-carboxylic Acid Using Methylene as the Protecting Group
Xu, Wanbin,Gong, Xudong,Odilov, Abdullajon,Hu, Tianwen,Jiang, Xiangrui,Zhu, Fuqiang,Guo, Shuang,Jiang, Dehui,Wu, Mingjun,Shen, Jingshan
, p. 2447 - 2452 (2021/11/13)
The development of an industrially scalable synthetic route for 5,7-dichlorotetrahydroisoquinoline-6-carboxylic acid (1), a key starting material for lifitegrast, is described. This route includes the following features: (1) tetrahydroisoquinoline19was pr
Synthesis method of lifitegrast intermediate 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline
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Paragraph 0086-0087; 0090, (2020/05/05)
The invention discloses a synthesis method of a lifitegrast intermediate 5,7-dichloro-1,2,3,4-tetrahydroisoquinoline, wherein the synthesis method comprises the steps: by using 2,4-dichlorobenzaldehyde as a starting material, carrying out nitro-alcohol co
