100129-92-8Relevant articles and documents
N-Amination of Pyrrole and Indole Heterocycles with Monochloramine (N H2Cl)
Hynes Jr., John,Doubleday, Wendel W.,Dyckman, Alaric J.,Godfrey Jr., Jollie D.,Grosso, John A.,Kiau, Susanne,Leftheris, Katerina
, p. 1368 - 1371 (2004)
A survey of several electrophilic ammonia reagents for the N-amination of indole- and pyrrole-containing heterocycles revealed that monochloramine (NH2Cl) is an excellent reagent for this transformation. Pyrroles and indoles containing a variety of substitution were aminated on nitrogen with isolated yields ranging from 45% to 97%.