4458-69-9

Basic information

• Product Name: diethyl 5-bromo-3-methyl-1H-pyrrole-2,4-dicarboxylate
• CAS NO: 4458-69-9
• Molecular Formula: C₁₁H₁₄BrNO₄
• Molecular Weight: 304.1372
• Mol File: 4458-69-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 405.5°C at 760 mmHg
• Flash Point: 199.1°C
• Density: 1.455g/cm³
• Vapor Pressure: 8.71E-07mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: diethyl 5-bromo-3-methyl-1H-pyrrole-2,4-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 5-bromo-3-methyl-1H-pyrrole-2,4-dicarboxylate(4458-69-9)
• EPA Substance Registry System: diethyl 5-bromo-3-methyl-1H-pyrrole-2,4-dicarboxylate(4458-69-9)

Safety Data

• Hazardous Substances Data: 4458-69-9(Hazardous Substances Data)

Upstream product

• 2199-60-2 diethyl 5-formyl-3-methylpyrrole-2,4-dicarboxylate 
• 37789-75-6 3,5-diethoxycarbonyl-4-methylpyrrole-2-carboxylic acid 
• 2436-79-5 diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate 

Downstream Products

• 5448-16-8 3-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester 
• 90610-57-4 3-methyl-pyrrole-2,4-dicarboxylic acid-2-ethyl ester 
• 3780-42-5 dimethyl 3-methyl-1H-pyrrole-2,4-dicarboxylate 
• 90610-58-5 4-ethoxycarbonyl-3-methylpyrrole-2-carboxylic acid 
• 3780-41-4 3-methyl-1H-pyrrole-2,4-dicarboxylic acid 
• 3284-47-7 ethyl 3-methyl-1H-pyrrole-2-carboxylate 
• 2199-49-7 ethyl 4-methylpyrrole-3-carboxylate 
• 40318-15-8 methyl 4-methyl-1H-pyrrole-3-carboxylate 
• 64276-66-0 4-methyl-1H-pyrrole-3-carboxylic acid 
• 100129-92-8 diethyl 5-chloro-3-methylpyrrole-2,4-dicarboxylate 

Relevant articles and documents

ELECTROPHILIC HETEROAROMATIC SUBSTITUTIONS. IX. BEHAVIOUR OF HALOGENOPYRROLES TOWARDS HYDROGEN HALIDES IN DIVERSE SOLVENTS

The reactions of a series of α- and β-bromo and-chloropyrroles with hydrogen halides have been investigated both in aprotic and protic solvents in order to establish the true nature of the processes.Proto dehalogenation (reductive dehalogenation) has only been observed in position α in aprotic solvents able to scavenge the elemental halogen (or mixed halogen) formed, whereas halogen exchange reactions are the prevailing processes under protic conditions.Contrary to previous statements, halogen exchange can occur in both directions (Cl--->Br and Br--->Cl) and has been observed only in α position.