2199-60-2

Basic information

• Product Name: 5-FORMYL-3-METHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID DIETHYL ESTER
• Synonyms: 5-FORMYL-3-METHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID DIETHYL ESTER;3-Methyl-5-formyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester;diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicarboxylate;diethyl 5-methanoyl-3-methyl-1H-pyrrole-2,4-dicarboxylate;4-Methyl-3,5-diethoxycarbonyl-2-forMylpyrrole;1H-Pyrrole-2,4-dicarboxylic acid, 5-forMyl-3-Methyl-, diethyl ester;2,4-Diethoxycarbonyl-3-methylpyrrol-5-carbaldehyde
• CAS NO: 2199-60-2
• Molecular Formula: C₁₂H₁₅NO₅
• Molecular Weight: 253.2512
• Mol File: 2199-60-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 439.7°Cat760mmHg
• Flash Point: 219.7°C
• Appearance: /
• Density: 1.238g/cm³
• Vapor Pressure: 6.23E-08mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: 5-FORMYL-3-METHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID DIETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 5-FORMYL-3-METHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID DIETHYL ESTER(2199-60-2)
• EPA Substance Registry System: 5-FORMYL-3-METHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID DIETHYL ESTER(2199-60-2)

Safety Data

• Hazardous Substances Data: 2199-60-2(Hazardous Substances Data)

Usage

General Description

5-FORMYL-3-METHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID DIETHYL ESTER is a chemical compound that belongs to the pyrrole-2,4-dicarboxylic acid ester family. It is commonly used in organic synthesis and pharmaceutical research due to its potential applications in drug development and the creation of novel organic compounds. The compound is a diethyl ester, meaning it contains two ester functional groups, and its structure includes a formyl group and a methyl group on a pyrrole ring. Its unique structure and functional groups make it a valuable building block for the synthesis of complex organic molecules and it is likely to be used in a wide range of applications within the chemical and pharmaceutical industries.

InChI:InChI=1/C12H15NO5/c1-4-17-11(15)9-7(3)10(12(16)18-5-2)13-8(9)6-14/h6,13H,4-5H2,1-3H3

Upstream product

• 2436-79-5 diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate 
• 52649-30-6 2-dichloromethyl-3,5-bisethoxycarbonyl-4-methylpyrrole 
• 7647-01-0 hydrogenchloride 
• 57745-26-3 diethyl 5-(bromomethyl)-3-methylpyrrole-2,4-dicarboxylate 
• 5422-89-9 3,5-bisethoxycarbonyl-2-hydroxymethyl-4-methylpyrrole 
• 64-19-7 acetic acid 
• 79830-01-6 5,10-(3,5-bisethoxycarbonyl-4-methylpyrrol-2-ylmethylenedioxy)-1,3,6,8-tetrakisethoxycarbonyl-2,7-dimethyl-5H,10H-dipyrrolo<1,2-a;1',2'-d>pyrazine 
• 1066-30-4 chromium(lll) acetate 

Downstream Products

• 37789-75-6 3,5-diethoxycarbonyl-4-methylpyrrole-2-carboxylic acid 
• 124857-38-1 (2S,3S)-1,4'-Dimethyl-5-phenyl-2,3-dihydro-1H,1'H-[2,2']bipyrrolyl-3,4,3',5'-tetracarboxylic acid 3',5'-diethyl ester 3,4-dimethyl ester 
• 124857-38-1 (2S,3R)-1,4'-Dimethyl-5-phenyl-2,3-dihydro-1H,1'H-[2,2']bipyrrolyl-3,4,3',5'-tetracarboxylic acid 3',5'-diethyl ester 3,4-dimethyl ester 
• 124857-35-8 4,1'-Dimethyl-3',5'-diphenyl-1H,1'H-[2,2']bipyrrolyl-3,5,4'-tricarboxylic acid 4'-benzyl ester 3,5-diethyl ester 
• 124890-68-2 4,1'-Dimethyl-4',5'-diphenyl-1H,1'H-[2,2']bipyrrolyl-3,5,3'-tricarboxylic acid 3'-benzyl ester 3,5-diethyl ester 
• 124857-28-9 ethyl 2-<(N-benzyl-N-methylamino)methyl>-3-(ethoxycarbonyl)-4-methylpyrrole-5-carboxylate 
• 5448-16-8 3-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester 
• 625-82-1 2,4-dimethyl-1H-pyrrole 
• 79754-46-4 3,5-bisethoxycarbonyl-2-formyl-1,4-dimethylpyrrole 
• 100129-92-8 diethyl 5-chloro-3-methylpyrrole-2,4-dicarboxylate 
• 124857-24-5 C₂₆H₃₂N₂O₅ 
• 124857-23-4 C₂₂H₂₆N₂O₄ 
• 5422-89-9 3,5-bisethoxycarbonyl-2-hydroxymethyl-4-methylpyrrole 
• 4458-69-9 diethyl 5-bromo-3-methylpyrrole-2,4-dicarboxylate 

Relevant articles and documents

Oxidation of pyrrole α-methyl to formyl with ceric ammonium nitrate

Pyrrole α-aldehydes can be prepared in high yield by oxidation of pyrrole α-methyl groups with ceric ammonium nitrate when the pyrrole ring also has an α-carboxylic acid ester group.

Imploded bilirubins: Synthesis and properties of 10-nor-mesobilirubin- XIIIα and analogs

Six 10-nor-bilirubin analogs have been synthesized and investigated. Lacking the C(10) CH2 group, these linear tetrapyrroles have a bipyrrole core rather than a dipyrrylmethane core and thus a different shape. Whereas the propionic acid groups

Pyrrole Studies. Part 26. A Novel Thermochromic and Photochromic Pyrrole System

2-Dichloromethyl-3,5-bisethoxycarbonyl-4-methylpyrrole (3) yields a thermally labile 5,10-methylenedioxy-5H,10H-dipyrrolopyrazine (1) when heated with 6percent aqueous potassium hydroxide.Upon being heated at 160 deg C the colourless dipyrrolopyrazine is converted into a red bis-(1-azafulvene) system, which can be reconverted photochemically into the dipyrrolopyrazine via a cycloaddition reaction.