10147-68-9Relevant articles and documents
The syntheses of nonnucleoside, HIV-1 reverse transcriptase inhibitors containing a CF2 group: The SRN1 reactions of 2-(bromodifluoromethyl)benzoxazole with the anions derived from heterocyclic thiols and phenolic compounds
Burkholder, Conrad R.,Dolbier Jr., William R.,Médebielle, Maurice
, p. 369 - 376 (2000)
In an effort to prepare new fluorine-containing compounds which are active against HIV, the SRN1 reactions of 2-(bromodifluoromethyl)benzoxazole (5) with the anions of heterocyclic thiols and phenolic compounds were carried out. The products (6
SYNTHESIS OF 2-(4-ARYL-1E,3E-BUTADIENYL)BENZOXAZOLES BY THE HORNER-WADSWORTH-EMMONS REACTION
Kosaka, Takatoshi,Wakabayashi, Toshio
, p. 477 - 486 (1995)
2-(4-Aryl-1E,3E-butadienyl)benzoxazole derivatives were synthesized by the Horner-Wadsworth-Emmons reaction of 2-phosphorylmethylbenzoxazoles with cinnamaldehydes in fair to good yield.
Synthesis, Molecular Docking and Biological Evaluation of 2-Aryloxy-N-Phenylacetamide and N′-(2-Aryloxyoxyacetyl) Benzohydrazide Derivatives as Potential Antibacterial Agents
Yele, Vidyasrilekha,Azam, Mohammad Afzal,Wadhwani, Ashish D.
, (2021/03/03)
A new class of 2-aryloxy-N-phenylacetamide and N′-(2-aryloxyoxyacetyl) benzohydrazide derivatives with different active moieties were synthesized and screened for their antibacterial activity. Structural characterization of synthesized compounds was perfo
Antidiabetic compounds
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Page/Page column 13-14, (2020/06/16)
Compounds for the treatment of hyperglycemia and/or diabetes are provided. The compounds, which inhibit the enzyme dipeptidyl peptidase (DPP-4), are based on the structure where X may be present or absent an may be OH, Ar is an aryl group; and n ranges from 0 to 5.